WormBase Tree Display for Expr_pattern: Expr14864
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| Expr14864 | Expression_of | Gene | WBGene00000396 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00000396 | |||
| Expression_data | Anatomy_term | WBbt:0004054 | Certain | |
| WBbt:0004056 | Certain | |||
| WBbt:0005739 | Certain | |||
| WBbt:0005753 | Certain | |||
| WBbt:0005829 | Certain | |||
| WBbt:0008115 | Certain | |||
| Type | In_situ | smFISH | ||
| Pattern | We also used smFISH to examine the expression of cdh-4 and cdh-3. Consistent with transgenic reporter studies (Sundararajan et al., 2014), we observed cdh-4 mRNA spots in the Q neuroblasts, as well as a wide range of other cells, including the neighboring seam and P cells, ventral nerve cord neurons and cells in the head region. In contrast, we found that during the initial polarization and migration phase, cdh-3 was specifically expressed in the Q neuroblasts, with additional expression only in a few unidentified cells in the head. Similar to unc-40, there was no significant difference in expression between QL and QR. Moreover, for both cdh-3 and cdh-4, the expression level correlated with migration distance (cdh-3 QL, Spearman r = 0.5765, p < 0.0001, QR, Spearman r = -0.4838, p < 0.0004; cdh-4 QL, Spearman r = 0.3176, p < 0.03, QR, Spearman r = -0.5070, p < 0.0004), indicating that expression increases during polarization and migration. | |||
| Reference | WBPaper00057287 |
