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WormBase Tree Display for Expr_pattern: Expr14915

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Name Class

Expr14915Expression_ofGeneWBGene00010755
Reflects_endogenous_expression_ofWBGene00010755
Expression_dataLife_stageWBls:0000041Anatomy_termWBbt:0003987
WBbt:0003989
WBbt:0005734
WBbt:0007849
WBbt:0007850
WBbt:0008435
WBls:0000023Anatomy_termWBbt:0003987
WBbt:0003989
WBbt:0005734
WBbt:0007849
WBbt:0007850
WBbt:0008435
Anatomy_termWBbt:0003987Certain
Life_stageWBls:0000023
WBls:0000041
WBbt:0003989Certain
Life_stageWBls:0000023
WBls:0000041
WBbt:0005734Certain
Life_stageWBls:0000023
WBls:0000041
WBbt:0007849Certain
Life_stageWBls:0000023
WBls:0000041
WBbt:0007850Certain
Life_stageWBls:0000023
WBls:0000041
WBbt:0008435Certain
Life_stageWBls:0000023
WBls:0000041
TypeGenome_editing
Reporter_gene
Patternvglu-2::gfp is dynamically expressed in a restricted set of distinct cell types. Within the nervous system, vglu-2::gfp is exclusively expressed in a single interneuron class, AIA, where it localizes to vesicular structures in the soma, but not along the axon, suggesting that VGLU-2 may not be involved in synaptic transport of glutamate. The expression in AIA can be observed throughout alllarval and adult stages in either hermaphrodite or male animals. Outside the nervous system, VGLU-2 is expressed in collagen-producing skin cells (syncytial epidermis and in uterine tissue) where it most prominently localizes to early endosomes, and to a lesser degree apical clathrin-coated pits, TGN, and late endosomes. On early endosomes VGLU-2 colocalized most strongly with the recycling promoting factor SNX-1, a retromer component.
ReferenceWBPaper00058928
VariationWBVar02152776