WormBase Tree Display for Expr_pattern: Expr15690
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Expr15690 | Expression_of | Gene | WBGene00002992 | ||
---|---|---|---|---|---|
Reflects_endogenous_expression_of | WBGene00002992 | ||||
Expression_data | Life_stage | WBls:0000027 | Anatomy_term | WBbt:0004522 | |
WBls:0000035 | Anatomy_term | WBbt:0004522 | |||
Anatomy_term | WBbt:0004522 | Certain | |||
Life_stage | WBls:0000027 | ||||
WBls:0000035 | |||||
GO_term | GO:0045180 | ||||
Type | Genome_editing | ||||
Reporter_gene | |||||
Pattern | In L2 and L3 larvae, mNGr::LIN-3 expression was detected in intracellular punctae and on the basal cortex of the AC. No extracellular mNGr::LIN-3 signal could be detected, suggesting that the majority of mNGr::LIN-3 remains attached to the AC surface after its secretion to the plasma membrane, or that a cleavage product of the mNGr::LIN-3 protein is released from the AC and rapidly taken up by the adjacent VPCs or degraded. The same localization pattern was observed with a multicopy GFP::LIN-3 transgene (zhIs67), in which the GFP tag had been inserted at the same position as in the endogenous mNGr::lin-3(zh112) reporter strain. In wild-type larvae, mNGr::LIN-3 was enriched towards the ventral cortex of the AC from the mid-L2 stage until the mid-L3 stage. | ||||
Reference | WBPaper00059670 | ||||
Variation | WBVar02149506 |