WormBase Tree Display for Expr_pattern: Expr16384
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| Expr16384 | Expression_of | Gene | WBGene00011444 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00011444 | |||
| Expression_data | Anatomy_term | WBbt:0004088 | Certain | |
| WBbt:0004090 | Certain | |||
| WBbt:0005739 | Certain | |||
| WBbt:0005741 | Certain | |||
| WBbt:0005753 | Certain | |||
| GO_term | GO:0005938 | |||
| GO:0005815 | ||||
| GO:0150002 | ||||
| Type | Genome_editing | |||
| Reporter_gene | ||||
| Pattern | We observed NOCA-2 accumulations in several spots in the head and tail of the animal and at the cortex of the epidermal seam cells. Indeed, using the NOCA-2 promoter to express mKate2, we observed a broad expression pattern. Importantly, we detected NOCA-2::GFP in the distal PVD dendrite during neuronal development, which showed a similar localization pattern and dynamics as GIP-2 and RAB-11. In order to validate that NOCA-2 localizes to the MTOC vesicles, we expressed mKate2::RAB-11 in the PVD and observed clear colocalization. In the mature neuron, we could not detect obvious NOCA-2 (nor GIP-2) accumulations at the dendrite tip, which agrees with the loss of distal EBP-2 dynamics. | |||
| Reference | WBPaper00064679 | |||
| Variation | WBVar02158844 |
