WormBase Tree Display for Expr_pattern: Expr2746
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Expr2746 | Expression_of (2) | ||
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Expression_data | GO_term | GO:0005884 | |
Subcellular_localization | In REF 52 fibroblasts UNC-87 localized to the actin stress fibers, and the ectopic expression of the UNC-87 protein caused a significant increase in stress fiber bundling. Moreover, stress fiber formation was significantly enhanced in the mouse melanoma cell line B16F1. | ||
Remark | Type: mammalian cell transfection. UNC-87 cDNA was cloned into the pEGFP C1 vector to generate a mutant protein fused to GFP at its amino terminus. Various cell lines were transfected with this construct, and the cellular localization was determined by fluorescence microscopy. | ||
Reference | WBPaper00004578 |