WormBase Tree Display for Expr_pattern: Expr2898
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| Expr2898 | Expression_of | Gene | WBGene00003845 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00003845 | |||
| Homol | Homol_homol | B0280:Expr | ||
| Expression_data | Life_stage | WBls:0000024 | ||
| WBls:0000003 | ||||
| WBls:0000038 | ||||
| WBls:0000027 | ||||
| WBls:0000035 | ||||
| Anatomy_term | WBbt:0005772 | Certain | ||
| Type | Reporter_gene | |||
| Pattern | Uniform expression of odd-1::GFP was detected in the intestine of embryos and larvae when the transgene was expressed from an extrachromosomal array. To more carefully assess odd-1::GFP localization, an integrated transgenic line was isolated and embryos from this line double-stained with antibodies specific for GFP and for the intestinal marker MH33. Uniform odd-1::GFP staining was detected in presumptive gut cells prior to the onset of elongation. However, unlike the more static pattern seen with the unstable extrachromosomal lines, differences in expression in the head and intestine were seen during elongation. The GFP signal increased in the most anterior cells of the intestine, and showed a concomitant relative decrease throughout the rest of the intestine, during the early stages of elongation. As elongation proceeded, additional GFP-positive cells were detected in the head. | |||
| Remark | Reporter gene fusion type not specified. | |||
| The observed expression pattern correlates well with the RNAi data, which point to a role for odd-1 in gut function and in cell specification in the head (probably in or associated with the pharynx). | ||||
| Reference | WBPaper00006353 | |||
| Transgene | WBTransgene00000320 |
