WormBase Tree Display for Expr_pattern: Expr3067
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Expr3067 | Expression_of | Gene | WBGene00001667 | |
---|---|---|---|---|
Reflects_endogenous_expression_of | WBGene00001667 | |||
Expression_data | Anatomy_term | WBbt:0003830 | Certain | |
WBbt:0003831 | Certain | |||
WBbt:0003995 | Certain | |||
WBbt:0003997 | Certain | |||
GO_term | GO:0030424 | |||
GO:0045202 | ||||
GO:0043025 | ||||
GO:0097730 | ||||
Subcellular_localization | Anti-GPA-5 antibodies were detected not only in the cilia, but also in the cell bodies and axons of the AWA neurons. Often, although faintly, staining was observed in the ADL cell bodies, but not in the ASI cells. A punctate staining pattern of the axon with anti-GPA-5 antibodies suggested that GPA-5 might be located at the synaptic sites of the AWA axons. Therefore, animals that expressed a snb-1::GFP fusion construct specifically in AWA was generated. Due to its fusion with SNB-1 synaptobrevin, green fluorescent protein (GFP) localizes to synaptic vesicles in these animals. Staining with anti-GPA-5 serum showed a punctate localization of GPA-5 close to SNB-1::GFP, suggesting that GPA-5 might function at the periactive zones of the AWA synapses. | |||
Type | Antibody | |||
Picture | WBPicture0000010910 | |||
Reference | WBPaper00024365 | |||
Antibody_info | WBAntibody00000771 |