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WormBase Tree Display for Expr_pattern: Expr3067

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Name Class

Expr3067Expression_ofGeneWBGene00001667
Reflects_endogenous_expression_ofWBGene00001667
Expression_dataAnatomy_termWBbt:0003830Certain
WBbt:0003831Certain
WBbt:0003995Certain
WBbt:0003997Certain
GO_termGO:0030424
GO:0045202
GO:0043025
GO:0097730
Subcellular_localizationAnti-GPA-5 antibodies were detected not only in the cilia, but also in the cell bodies and axons of the AWA neurons. Often, although faintly, staining was observed in the ADL cell bodies, but not in the ASI cells. A punctate staining pattern of the axon with anti-GPA-5 antibodies suggested that GPA-5 might be located at the synaptic sites of the AWA axons. Therefore, animals that expressed a snb-1::GFP fusion construct specifically in AWA was generated. Due to its fusion with SNB-1 synaptobrevin, green fluorescent protein (GFP) localizes to synaptic vesicles in these animals. Staining with anti-GPA-5 serum showed a punctate localization of GPA-5 close to SNB-1::GFP, suggesting that GPA-5 might function at the periactive zones of the AWA synapses.
TypeAntibody
PictureWBPicture0000010910
ReferenceWBPaper00024365
Antibody_infoWBAntibody00000771