WormBase Tree Display for Expr_pattern: Expr3425
expand all nodes | collapse all nodes | view schema
Expr3425 | Expression_of | Gene | WBGene00000995 | |
---|---|---|---|---|
Reflects_endogenous_expression_of | WBGene00000995 | |||
Expression_data | Anatomy_term | WBbt:0003826 | Certain | |
WBbt:0003827 | Certain | |||
WBbt:0003889 | Certain | |||
WBbt:0003890 | Certain | |||
WBbt:0003903 | Certain | |||
WBbt:0003904 | Certain | |||
WBbt:0003999 | Certain | |||
WBbt:0004003 | Certain | |||
WBbt:0005733 | Certain | |||
Type | Reporter_gene | |||
Pattern | A die-1::gfp reporter gene, which rescues the lsy defect, shows a dynamic expression profile with early hypodermal expression ceasing at gastrulation and then reappearing in late embryos in several putative head neurons. Using an ASE-neuron-expressed red-fluorescent-protein reporter (ceh-36prom::rfp), two of these neurons were identified as ASEL and ASER. However, expression is strongly biased towards ASEL. Besides ASE expression, consistent and strong expression of gfp from the otIs159 array is also observed in the ASH, ADF and AWC neurons. | |||
Remark | Reporter gene fusion type not specified. | |||
The autonomous function of die-1 in the mature ASEL neurons was corroborated by expressing the die-1 complementary DNA under the control of the promoter of the ASEL-specific gcy-7 gene. When expressed in a die-1 mutant background, three of four lines showed rescue of the lsy phenotype. | ||||
Reference | WBPaper00024291 | |||
Transgene | WBTransgene00001614 |