WormBase Tree Display for Expr_pattern: Expr3689

Expr3689 Expression_of: Gene: WBGene00000934
    Reflects_endogenous_expression_of: WBGene00000934
  Expression_data: Anatomy_term: WBbt:0004007 Certain
      WBbt:0004009 Certain
      WBbt:0004931 Certain
      WBbt:0004933 Certain
      WBbt:0004937 Certain
      WBbt:0004938 Certain
    GO_term: GO:0005886
      GO:0030425
      GO:0030424
      GO:0043025
  Subcellular_localization: Expression of GFP:DAT-1 was observed along the plasma membrane of the CEP and ADE cell somas, out along dendrites, and in axons terminating in synapses localized to the nerve ring.
  Type: Reporter_gene
  Pattern: Animals produced expressing the wild-type DAT-1 translational fusion (BY312 vtIs6 [Pdat-1::GFP:DAT-1; rol-6]), displayed a readily detectable level of expression in all dopaminergic head neurons (CEP, ADE). This expression pattern is consistent with the DA neuron-specific expression of a dat-1 transcriptional fusion (BY200), described previously (see Paper cgc5147).
  Remark: The GFP:DAT-1 fusion is functional in vivo since it fully restores 6-OHDA sensitivity to a (BY329 dat-1(ok157); vtIs6; vtIs7).
  Reference: WBPaper00026637
  Transgene: WBTransgene00004907