WormBase Tree Display for Expr_pattern: Expr3750
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Expr3750 | Expression_of (2) | |
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Expression_data (3) | ||
Subcellular_localization | As the embryo develops, FUS-1 levels increase in these epidermal cells, where it concentrates almost exclusively on the apical membrane and some colocalizes with apical junctions. | |
Type | Antibody | |
Pattern | Anti-FUS-1 antibody first detects FUS-1 in a punctate pattern within the gut cells of embryos at approximately the comma stage (~6 hr pf); it is undetectable in epidermal cells at this early stage. FUS-1 is also detected in the excretory cell and the apical membrane of gut cells starting later in embryogenesis. In the epidermis, the protein is first conspicuously detected in 2-fold stage embryos shortly after most epidermal cell fusions occur. Initially, FUS-1 expression is seen at approximately equal levels throughout the dorsal, ventral, and anterior epidermal cells; it is specifically excluded from the lateral seam cells. FUS-1 remains virtually undetectable in seam cells, which neither fuse in wild-type embryos and fus-1 mutants nor express EFF-1. | |
Picture | WBPicture0000009973 | |
Reference | WBPaper00026591 | |
Antibody_info | WBAntibody00000847 |