WormBase Tree Display for Expr_pattern: Expr4795
expand all nodes | collapse all nodes | view schema
| Expr4795 | Expression_of | Gene | WBGene00001816 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00001816 | |||
| Expression_data | Anatomy_term | WBbt:0005772 | Certain | |
| WBbt:0005784 | Certain | |||
| GO_term | GO:0030176 | |||
| Subcellular_localization | In double-labeling experiments, the anti-HAF-6 antibody did not decorate the same cellular compartment as a mitochondrial antibody (anti-Complex IV). Authors did observe co-compartmentalization using anti-HAF-6 and anti-Calreticulin antibodies, indicating that HAF-6 likely resides in the endoplasmic reticulum and not in mitochondria. HAF-6 localization extended to perinuclear regions in germline tissue, which is consistent with an endoplasmic reticulum (ER) localization. However, localization of HAF-6 to the nuclear periphery was not prominent in intestinal tissue. | |||
| Type | Antibody | |||
| Pattern | HAF-6 was predominantly expressed in intestinal and germline tissue. | |||
| Picture | WBPicture0000008801 | |||
| Remark | The subcellular patterns observed in experiments using anti-HAF-6 antibody were similar to the patterns of GFP expression observed in transgenic animals expressing the HAF-6::GFP fusion protein. | |||
| Reference | WBPaper00027644 | |||
| Antibody_info | WBAntibody00001096 |
