WormBase Tree Display for Expr_pattern: Expr8618
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| Expr8618 | Expression_of | Gene | WBGene00020091 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00020091 | |||
| Expression_data | Anatomy_term | WBbt:0005784 | Certain | |
| GO_term | GO:0005737 | |||
| GO:0043186 | ||||
| Subcellular_localization | Immunostaining revealed that RNP-8L protein is predominantly cytoplasmic, colocalizes with the PGL-1 germ granule marker, and is abundant in the proximal pachytene region and developing oocytes. RNP-8L was detectable in males, but much less abundant than in hermaphrodites. As assessed by immunocytochemistry of male germlines, RNP-8L was limited to the mitotic region, transition zone, and distal pachytene region; it was absent from proximal pachytene cells, spermatocytes, and mature sperm. RNP-8L was similar in both hermaphrodite and male distal germlines, both with respect to its low level and its distribution in cytoplasmic granules. As assessed by western blot, RNP-8L was also low in mutant adult hermaphrodites that made only sperm and no oocytes. Abundant RNP-8L seem to be associated with oogenesis. | |||
| Type | Antibody | |||
| Picture | WBPicture0000010045 | |||
| Remark | Picture: 3H to 3M. | |||
| Reference | WBPaper00033205 | |||
| Antibody_info | WBAntibody00001926 |
