WormBase Tree Display for Expr_pattern: Expr8869
expand all nodes | collapse all nodes | view schema
Expr8869 | Expression_of (2) | |
---|---|---|
Expression_data (2) | ||
Subcellular_localization | HIM-18 is first observed in mitotic nuclei at the distal tip region of the germline (premeiotic tip). However, the HIM-18 signal is abruptly reduced as nuclei enter into meiotic prophase, being barely visible in the transition zone (leptotene/zygotene) or in early to mid pachytene nuclei. HIM-18 signal is then clearly detected once again in late pachytene nuclei, persisting through the end of diakinesis. At a higher resolution, the HIM-18 signal is observed as nuclear foci (mainly around the chromosomes) in the premeiotic tip, late pachytene and diplotene/diakinesis stages. Although the HIM-18 signal is reduced from transition zone through mid-pachytene, a low level of HIM-18 foci, both on and around chromosomes, is still apparent at these stages upon longer exposure. Finally, HIM-18 is no longer observed localizing onto chromosomes after diakinesis. | |
Type | Antibody | |
Picture | WBPicture0000007424 | |
Remark | Picture: Figure 1C. | |
Reference | WBPaper00035505 | |
Antibody_info | WBAntibody00002070 |