WormBase Tree Display for Expr_pattern: Expr8901
expand all nodes | collapse all nodes | view schema
| Expr8901 | Expression_of | Gene | WBGene00004927 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004927 | |||
| Expression_data | Life_stage | WBls:0000024 | ||
| WBls:0000038 | ||||
| WBls:0000027 | ||||
| WBls:0000035 | ||||
| WBls:0000041 | ||||
| WBls:0000015 | ||||
| WBls:0000021 | ||||
| WBls:0000010 | ||||
| WBls:0000013 | ||||
| Anatomy_term | WBbt:0005733 | Certain | ||
| WBbt:0005751 | Certain | |||
| WBbt:0005772 | Certain | |||
| WBbt:0005813 | Certain | |||
| WBbt:0005828 | Certain | |||
| GO_term | GO:0005737 | |||
| GO:0009986 | ||||
| Subcellular_localization | Although primarily localized in the cytoplasm, SNX-1::GFP was also found to be enriched around both embryonic and germ cell corpses, displaying ring-like or punctate structures. These observations suggest that SNX-1 is likely recruited to the surface of cell corpses during the process of cell corpse clearance. Interestingly, the corpse-surface localization of SNX-1::GFP is dependent on the cell corpse stage. For example, SNX-1::GFP encircles early stage germ cell corpses but not late stage corpses, suggesting that SNX-1/retromer likely acts during early steps of cell corpse removal. | |||
| Type | Reporter_gene | |||
| Pattern | SNX-1::GFP expression is ubiquitous in early embryos at the ~50-cell stage and appears to be cytoplasmic. At larval stages, SNX-1::GFP is expressed in many cell types responsible for engulfing somatic cell corpses, including hypodermal, intestinal and body wall muscle cells. In adult animals, SNX-1::GFP is also seen in gonadal sheath cells that function to engulf germ cell corpses, and coelomocytes. | |||
| Remark | Picture: Fig. S7. | |||
| Reference | WBPaper00035888 | |||
| Transgene | WBTransgene00030786 |
