WormBase Tree Display for Expr_pattern: Expr9176
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| Expr9176 | Expression_of | Gene | WBGene00019345 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00019345 | |||
| Expression_data | Life_stage | WBls:0000024 | ||
| WBls:0000003 | ||||
| WBls:0000038 | ||||
| WBls:0000027 | ||||
| WBls:0000035 | ||||
| WBls:0000041 | ||||
| Anatomy_term | WBbt:0003681 | Certain | ||
| WBbt:0005730 | Certain | |||
| WBbt:0005772 | Certain | |||
| GO_term | GO:0005811 | |||
| Subcellular_localization | The lipophilic dyes Nile Red and Mitotracker Red were used to assess the co-localization of TMEM-135 with fat droplets or mitochondria, respectively. No co-localization of TMEM-135::GFP and Mito- Tracker Red (mitochondrial) was observed in the worm, whereas TMEM-135::GFP and Nile Red displayed very strong colocalization. Data provide strong evidence that the TMEM135 protein is associated with fat droplets. | |||
| Type | Reporter_gene | |||
| Pattern | In the tmem-135 promoter::GFP-expressing strain, as well as in the eight independent TMEM-135::GFP-expressing strains, ubiquitous expression from the pretzel embryo to the adult stage was observed, despite mozaicism due to the extra-chromosomal array. More specifically, tmem-135 expression was more strongly expressed in the lower intestine and in the pharynx. TMEM- 135::GFP showed a high level of expression throughout the entire length of the intestine, as well as in all epithelia. | |||
| Picture | WBPicture0000007775 | |||
| WBPicture0000007777 | ||||
| Reference | WBPaper00037872 | |||
| Transgene | WBTransgene00030953 |
