WormBase Tree Display for GO_term: GO:0000124
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| GO:0000124 | Name | SAGA complex | |
|---|---|---|---|
| Definition | A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695). | ||
| Alt_id | GO:0000125 | ||
| GO:0030914 | |||
| Synonym | Exact | Spt-Ada-Gcn5-acetyltransferase complex | |
| Narrow | PCAF complex | ||
| PCAF histone acetylase-associated complex | |||
| SPT3-TAF9-PCAF acetylase complex | |||
| Related | SPT3-TAF9-GCN5 acetylase complex | ||
| STAGA coactivator complex | |||
| STAGA complex | |||
| Status | Valid | ||
| Type | Cellular_component | ||
| Parent | Instance_of | GO:0070461 | |
| GO:1905368 | |||
| Attributes_of | Motif | INTERPRO:IPR018783 | |
| INTERPRO:IPR021950 | |||
| INTERPRO:IPR037782 | |||
| INTERPRO:IPR037794 | |||
| INTERPRO:IPR037796 | |||
| INTERPRO:IPR037802 | |||
| INTERPRO:IPR037804 | |||
| INTERPRO:IPR039460 | |||
| Index | Ancestor (19) | ||
| GO_annotation (65) | |||
| Version | Gene Ontology releases/2023-11-15 |
