WormBase Tree Display for GO_term: GO:0030122
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| GO:0030122 | Name | AP-2 adaptor complex | |
|---|---|---|---|
| Definition | A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). | ||
| Synonym | Exact | HA2 | |
| HA2 clathrin adaptor | |||
| Status | Valid | ||
| Type | Cellular_component | ||
| Parent | Instance_of | GO:0098797 | |
| GO:0030131 | |||
| Component_of | GO:0030132 | ||
| GO:0030128 | |||
| Attributes_of | Motif | INTERPRO:IPR017104 | |
| INTERPRO:IPR027156 | |||
| Index | Ancestor (41) | ||
| GO_annotation (26) | |||
| Version | Gene Ontology releases/2023-11-15 |
