WormBase Tree Display for GO_term: GO:0120123

GO:0120123 Name: ubiquitin activating enzyme complex
  Definition: A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.
  Synonym: Exact: E1 complex
    Related: E1 ubiquitin-activating enzyme
  Status: Valid
  Type: Cellular_component
  Parent: Instance_of: GO:1902494
      GO:0140535
  Attributes_of: Index: Ancestor: GO:0005575
        GO:0032991
        GO:1902494
        GO:0140535
  Version: Gene Ontology releases/2023-11-15