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WormBase Tree Display for Gene: WBGene00000047

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Name Class

WBGene00000047SMapS_parentSequenceZC504
IdentityVersion1
NameCGC_nameacr-8Person_evidenceWBPerson1430
Sequence_nameZC504.2
Molecular_nameZC504.2
ZC504.2.1
CE53615
ZC504.2.2
Other_nameCELE_ZC504.2Accession_evidenceNDBBX284606
Public_nameacr-8
DB_infoDatabase (10)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:19WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classacr
AlleleWBVar01759166
WBVar00092488
WBVar01759167
WBVar01759168
WBVar02139982
WBVar02139983
WBVar01487574
WBVar01694294
WBVar01711114
WBVar01180925
WBVar01180926
WBVar01180927
WBVar01180928
WBVar01180929
WBVar01981237
WBVar01180930
WBVar01180931
WBVar01180932
WBVar01180933
WBVar01180934
WBVar01180935
WBVar01180936
WBVar01180937
WBVar01527651
WBVar01180938
WBVar01180939
WBVar01180940
WBVar01180941
WBVar01180942
WBVar01180943
WBVar01180944
WBVar01180945
WBVar01928143
WBVar01928144
WBVar00064611
WBVar00515058
WBVar00515059
WBVar00515060
WBVar00515061
WBVar00515062
WBVar00515063
WBVar00515064
WBVar00515065
WBVar00515066
WBVar00515067
WBVar01987633
WBVar01888769
WBVar01551808
WBVar01901574
WBVar00063484
WBVar00082490
WBVar01498960
WBVar01500067
StrainWBStrain00031896
RNASeq_FPKM (74)
GO_annotation (27)
Ortholog (77)
Paralog (100)
Structured_descriptionConcise_descriptionacr-8 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR); ACR-8 falls into the 'ACR-8' class of nAChR subunits, which includes ACR-12 and ACR-13.Paper_evidenceWBPaper00005223
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in body wall musculature; enteric muscle; nerve ring; neurons; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including congenital myasthenic syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit); and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (30)
Molecular_infoCorresponding_CDSZC504.2
Corresponding_CDS_historyZC504.2:wp54
ZC504.2:wp124
ZC504.2:wp272
Corresponding_transcriptZC504.2.1
ZC504.2.2
Other_sequence (16)
Associated_featureWBsf718691
WBsf1006700
Experimental_infoRNAi_resultWBRNAi00058977Inferred_automaticallyRNAi_primary
Expr_patternExpr3704
Expr4340
Expr4979
Expr1012528
Expr1030022
Expr1162412
Expr2009197
Expr2027435
Drives_construct (11)
Construct_productWBCnstr00006479
WBCnstr00006480
WBCnstr00011615
WBCnstr00037770
Microarray_results (19)
Expression_cluster (122)
InteractionWBInteraction000133959
WBInteraction000136793
WBInteraction000142026
WBInteraction000144320
WBInteraction000209431
WBInteraction000504009
WBInteraction000518504
WBInteraction000543443
Map_infoMapXPosition2.18612Error0.001806
PositivePositive_cloneZC504Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4886
4909
Pseudo_map_position
Reference (28)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene