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WormBase Tree Display for Gene: WBGene00001413

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Name Class

WBGene00001413SMapS_parentSequenceC01F6
IdentityVersion1
NameCGC_namefem-3Person_evidenceWBPerson261
Sequence_nameC01F6.4
Molecular_nameC01F6.4a
C01F6.4a.1
CE02953
C01F6.4c
CE46813
C01F6.4b
C01F6.4c.1
Other_nameCELE_C01F6.4Accession_evidenceNDBBX284604
Public_namefem-3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfem
Reference_alleleWBVar00144465
WBVar00240985
AlleleWBVar00144465Inferred_automaticallyFrom strain object: CB3843
From strain object: JK3965
WBVar00144475Inferred_automaticallyFrom strain object: CB3844
WBVar00144468Inferred_automaticallyFrom strain object: CB4015
WBVar00240985Inferred_automaticallyFrom strain object: CB4760
From strain object: JK816
From strain object: JK860
WBVar00144514
WBVar00144771
WBVar00144709
WBVar00144531
WBVar00240988
WBVar00144420
WBVar00144464
WBVar00144450
WBVar00144510
WBVar00144539
WBVar00144476
WBVar00144479
WBVar00144512
WBVar00144509
WBVar00144487
WBVar00144770
WBVar00144453
WBVar00144505
WBVar00144452
WBVar00144473
WBVar00144504
WBVar00144615
WBVar00144449
WBVar00144777
WBVar00091295
WBVar00431604
WBVar00431605
WBVar00431606
WBVar00431607
WBVar00431608
WBVar00431609
WBVar01500079
WBVar01730350
WBVar01730351
WBVar02114921
WBVar01498996
WBVar00144506
WBVar00144532
WBVar00144537
WBVar00144592
WBVar01499228
WBVar02134373
WBVar01855417
WBVar01855418
WBVar01855419
WBVar02036998
WBVar01498928
WBVar00930195
WBVar00930196
WBVar00930197
WBVar00930198
WBVar00240986
WBVar00930199
WBVar00930200
WBVar00240987
WBVar00930201
WBVar00930202
WBVar00930203
WBVar01453578
WBVar00930204
WBVar01453579
WBVar00930205
WBVar00930206
WBVar00241010
WBVar00241011
WBVar01500245
WBVar00252640
Legacy_informationClass 1 (loss-of-function) : e1996sd mat : XO animals transformed into fertile females if mother homozygous e1996 into intersexes if mother heterozygous e1996/+; XX animals fertile females. Some e1996/+ XX animals female. Some e1996/+ sons of e1996 mothers are feminized. ES3 (XO adult) ES2 (XX adult). ME0. NA > 20 (e1950 e2006ts : XX self-fertile at 20x).
Class 2 (gain-of-function) : q20sd ts : at 25x XX germline makes only sperm at 15x XX germline makes oocytes and excess sperm. ES3 (progeny) ME3. NA9 (q24 etc. : all ts).
See also e1950, e1980, e1981, e1983, e1984, e1995, e1996, e1999, e2004, e2006, e2007, e2010, e2043, e2045, e2062, e2063, e2068, e2070, e2143, e2178, e2289, e2353, e2354, e2366
[C.elegansII] e1996sd,mat,och : XO animals transformed into fertile females if mother homozygous, into intersexes if mother heterozygous; XX animals fertile females. Some e1996/+ XX animals female. Some e1996/+ sons of e1996 mothers are feminized. ES3 (XO adult) ES2 (XX adult). ME0. OA>20 e1950, e2068amb, e2006ts (XX self-fertile at 20C). Also gf,ts alleles, q20sd,ts (at 25C XX germline makes only sperm, at 15C XX germline makes oocytes and excess sperm. ES3 (progeny) ME3. OA8(gf):q22ts (weaker), q95ts (strongest allele, 80% Mog even at 15C). Cloned: 1.7 kb and 1.55 kb (minor) transcripts, former encodes predicted 388 aa novel protein. gf alleles are alterations in 3'UTR. Transgene overexpression of fem-3 leads to extensive masculinization of XX soma. [Hodgkin 1986; Ahringer et al. 1992; CB; JK; AS]
Strain (12)
RNASeq_FPKM (74)
GO_annotation (26)
Ortholog (21)
Structured_descriptionConcise_descriptionfem-3 encodes a novel protein that promotes male development in all tissues.Paper_evidenceWBPaper00001378
Curator_confirmedWBPerson1843
Date_last_updated11 Apr 2005 00:00:00
Automated_descriptionEnables protein phosphatase binding activity. Involved in several processes, including protein localization to chromatin; regulation of reproductive process; and sex determination. Located in cytoplasm and protein-containing complex. Expressed in germ line; spermatid; and in male.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDS (2)
Corresponding_transcriptC01F6.4b
C01F6.4a.1
C01F6.4c.1
Other_sequenceX64962
CBC07169_1
Associated_featureWBsf660472
WBsf997355
WBsf1017925
WBsf228786
Experimental_infoRNAi_resultWBRNAi00061018Inferred_automaticallyRNAi_primary
WBRNAi00030242Inferred_automaticallyRNAi_primary
WBRNAi00039313Inferred_automaticallyRNAi_primary
WBRNAi00087453Inferred_automaticallyRNAi_primary
WBRNAi00007588Inferred_automaticallyRNAi_primary
WBRNAi00081939Inferred_automaticallyRNAi_primary
WBRNAi00081938Inferred_automaticallyRNAi_primary
WBRNAi00085808Inferred_automaticallyRNAi_primary
Expr_patternExpr1382
Expr3829
Expr9317
Expr1021877
Expr1030847
Expr1143426
Expr2011751
Expr2029989
Drives_constructWBCnstr00011680
WBCnstr00018576
WBCnstr00036963
Construct_product (17)
AntibodyWBAntibody00002227
WBAntibody00002344
Microarray_results (21)
Expression_cluster (154)
Interaction (421)
WBProcessWBbiopr:00000110
Map_infoMapIVPosition4.04953Error0.001985
Well_ordered
PositiveInside_rearreDf18
eDf19
Positive_cloneC01F6Inferred_automaticallyFrom sequence, transcript, pseudogene data
JK#2
Mapping_data2_point1640
Multi_point (14)
Pos_neg_data959
964
972
Landmark_gene
Reference (401)
PictureWBPicture0000013095
MethodGene