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WormBase Tree Display for Gene: WBGene00002023

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Name Class

WBGene00002023SMapS_parentSequenceC09B8
IdentityVersion1
NameCGC_namehsp-25Person_evidenceWBPerson36
Sequence_nameC09B8.6
Molecular_nameC09B8.6a
C09B8.6a.1
CE02466
C09B8.6b
CE33558
C09B8.6c
CE37953
C09B8.6b.1
C09B8.6c.1
C09B8.6c.2
Other_nameHSP25Paper_evidenceWBPaper00036199
CELE_C09B8.6Accession_evidenceNDBBX284606
Public_namehsp-25
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhsp
AlleleWBVar01830633
WBVar00079595
WBVar00079596
WBVar00079597
WBVar00079599
WBVar00079600
WBVar00079601
WBVar00079602
WBVar00079603
WBVar01487030
WBVar00249730
WBVar02064132
WBVar01945498
WBVar01945499
WBVar01526528
WBVar02150183
WBVar02086813
WBVar01151479
WBVar00097834
WBVar01880611
WBVar01151480
WBVar01880612
WBVar01151481
WBVar01151482
WBVar01151483
WBVar01151484
WBVar01151485
WBVar01151486
WBVar01550096
WBVar01151487
WBVar01550097
WBVar01151488
WBVar01550098
WBVar01151489
WBVar01550099
WBVar01151490
WBVar01550100
WBVar01151491
WBVar01550101
WBVar01151492
WBVar01550102
WBVar01550103
WBVar01151493
WBVar01151494
WBVar01550104
WBVar01151495
WBVar01926873
WBVar01550105
WBVar01151496
WBVar01550106
WBVar01926874
WBVar01151497
WBVar01151498
WBVar01941419
WBVar01151499
WBVar01941420
WBVar01151500
WBVar01151501
WBVar01498888
WBVar01151502
WBVar01151503
WBVar01151504
WBVar01151505
WBVar01151506
WBVar01151507
WBVar01151508
WBVar01151509
WBVar01151510
WBVar01151511
WBVar01151512
WBVar01151513
WBVar01151514
WBVar01758576
WBVar01758577
WBVar02070383
WBVar00505176
WBVar00505177
WBVar00505178
WBVar00505179
WBVar00033171
WBVar01500067
RNASeq_FPKM (74)
GO_annotation00059380
00059381
00059382
00059383
00059384
00059385
00059386
Ortholog (35)
Paralog (17)
Structured_descriptionConcise_descriptionhsp-25 encodes a member of the small heat shock family of proteins; HSP-25 is expressed throughout development and in vitro, exhibits chaperone activity; HSP-25 localizes to: 1) dense bodies and M lines in body wall muscle, 2) the lining of the pharynx, and 3) to cell-cell junctions in the spermathecal wall; consistent with a role in myofibril organization, HSP-25 binds vinculin and alpha-actinin in vitro.Paper_evidenceWBPaper00003970
WBPaper00013029
Curator_confirmedWBPerson1843
Date_last_updated02 Mar 2007 00:00:00
Automated_descriptionPredicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Located in M band and striated muscle dense body. Expressed in body wall musculature; gonad; pharynx; and spermatheca. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and distal hereditary motor neuronopathy type 2A. Is an ortholog of human HSPB8 (heat shock protein family B (small) member 8).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111208Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:30171)
DOID:0110174Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:30171)
Molecular_infoCorresponding_CDSC09B8.6a
C09B8.6b
C09B8.6c
Corresponding_transcriptC09B8.6a.1
C09B8.6b.1
C09B8.6c.1
C09B8.6c.2
Other_sequence (120)
Associated_feature (19)
Experimental_infoRNAi_resultWBRNAi00097033Inferred_automaticallyRNAi_primary
WBRNAi00106387Inferred_automaticallyRNAi_primary
WBRNAi00076103Inferred_automaticallyRNAi_primary
WBRNAi00040161Inferred_automaticallyRNAi_primary
WBRNAi00033415Inferred_automaticallyRNAi_primary
WBRNAi00010508Inferred_automaticallyRNAi_primary
Expr_patternExpr1087
Expr1088
Expr4163
Expr15507
Expr1018056
Expr1031178
Expr1144237
Expr2012624
Expr2030860
Drives_constructWBCnstr00036514
WBCnstr00042198
Construct_productWBCnstr00036514
WBCnstr00042198
AntibodyWBAntibody00000270
Microarray_results (33)
Expression_cluster (201)
Interaction (48)
Map_infoMapXPosition-3.82033Error0.011016
PositivePositive_cloneC09B8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4562
Pseudo_map_position
ReferenceWBPaper00013029
WBPaper00036199
WBPaper00038491
WBPaper00055090
WBPaper00060685
WBPaper00061766
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene