WormBase Tree Display for Gene: WBGene00004782
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| WBGene00004782 | SMap | S_parent | Sequence | C26E6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | set-2 | Person_evidence | WBPerson632 | |||||
| Sequence_name | C26E6.9 | ||||||||
| Molecular_name | C26E6.9a | ||||||||
| C26E6.9a.1 | |||||||||
| CE27735 | |||||||||
| C26E6.9b | |||||||||
| CE01158 | |||||||||
| C26E6.9c | |||||||||
| CE27736 | |||||||||
| C26E6.9b.1 | |||||||||
| C26E6.9c.1 | |||||||||
| Other_name | CELE_C26E6.9 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | set-2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | set | ||||||||
| Allele | WBVar00601264 | ||||||||
| WBVar00824707 | |||||||||
| WBVar00824708 | |||||||||
| WBVar00824709 | |||||||||
| WBVar00824710 | |||||||||
| WBVar00824711 | |||||||||
| WBVar00090872 | |||||||||
| WBVar00092223 | |||||||||
| WBVar01900734 | |||||||||
| WBVar01710013 | |||||||||
| WBVar01893322 | |||||||||
| WBVar01644400 | |||||||||
| WBVar01644401 | |||||||||
| WBVar01644402 | |||||||||
| WBVar00602637 | |||||||||
| WBVar00602638 | |||||||||
| WBVar01479724 | |||||||||
| WBVar01408539 | |||||||||
| WBVar00396922 | |||||||||
| WBVar00396923 | |||||||||
| WBVar00396924 | |||||||||
| WBVar02131947 | |||||||||
| WBVar00396925 | |||||||||
| WBVar00396926 | |||||||||
| WBVar00396927 | |||||||||
| WBVar00396928 | |||||||||
| WBVar00092697 | |||||||||
| WBVar00396929 | |||||||||
| WBVar00396930 | |||||||||
| WBVar00396931 | |||||||||
| WBVar00396932 | |||||||||
| WBVar00396933 | |||||||||
| WBVar00396934 | |||||||||
| WBVar00092704 | |||||||||
| WBVar00396935 | |||||||||
| WBVar01263246 | |||||||||
| WBVar01263247 | |||||||||
| WBVar01263248 | |||||||||
| WBVar01263252 | |||||||||
| WBVar02151183 | |||||||||
| WBVar01263253 | |||||||||
| WBVar01263254 | |||||||||
| WBVar01496522 | |||||||||
| WBVar01445520 | |||||||||
| WBVar01445524 | |||||||||
| WBVar00824665 | |||||||||
| WBVar01656582 | |||||||||
| WBVar00824666 | |||||||||
| WBVar00052456 | |||||||||
| WBVar00824667 | |||||||||
| WBVar00824668 | |||||||||
| WBVar00824669 | |||||||||
| WBVar00824670 | |||||||||
| WBVar00824671 | |||||||||
| WBVar00824672 | |||||||||
| WBVar00824673 | |||||||||
| WBVar00824674 | |||||||||
| WBVar00824675 | |||||||||
| WBVar00824676 | |||||||||
| WBVar00824677 | |||||||||
| WBVar00824678 | |||||||||
| WBVar00824679 | |||||||||
| WBVar00824680 | |||||||||
| WBVar00824681 | |||||||||
| WBVar01983893 | |||||||||
| WBVar00824682 | |||||||||
| WBVar00824683 | |||||||||
| WBVar01908414 | |||||||||
| WBVar00824684 | |||||||||
| WBVar00824685 | |||||||||
| WBVar00824686 | |||||||||
| WBVar00824687 | |||||||||
| WBVar00824688 | |||||||||
| WBVar00824689 | |||||||||
| WBVar00824690 | |||||||||
| WBVar00824691 | |||||||||
| WBVar00824692 | |||||||||
| WBVar00824693 | |||||||||
| WBVar00824694 | |||||||||
| WBVar00824695 | |||||||||
| WBVar00250609 | |||||||||
| WBVar00824696 | |||||||||
| WBVar00824697 | |||||||||
| WBVar00824698 | |||||||||
| WBVar00824699 | |||||||||
| WBVar00824700 | |||||||||
| WBVar00824701 | |||||||||
| WBVar00824702 | |||||||||
| WBVar00824703 | |||||||||
| WBVar00824704 | |||||||||
| WBVar00824705 | |||||||||
| WBVar00824706 | |||||||||
| Strain | WBStrain00027489 | ||||||||
| WBStrain00031733 | |||||||||
| WBStrain00032046 | |||||||||
| WBStrain00036215 | |||||||||
| WBStrain00000040 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Contained_in_operon | CEOP3240 | ||||||||
| Ortholog (40) | |||||||||
| Paralog (19) | |||||||||
| Structured_description | Concise_description | set-2 encodes a histone H3K4 methyltransferase closely related to the yeast Set1 and mammalian SET1/MLL proteins; SET-2 displays H3K4 methyltransferase activity in vitro and in C. elegans, regulates levels of H3K4; SET-2 plays a role in germline development, postembryonic development, negative regulation of lifespan in adult animals, and RNA interference; SET-2 localizes to nuclei. | Paper_evidence | WBPaper00005020 | |||||
| WBPaper00032309 | |||||||||
| WBPaper00036383 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 21 Sep 2010 00:00:00 | ||||||||
| Automated_description | Enables histone H3K4 methyltransferase activity. Involved in determination of adult lifespan and transdifferentiation. Located in nucleus. Expressed in several structures, including germ line; hermaphrodite distal tip cell; intestine; and nerve ring. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with speech impairment and dysmorphic facies. Is an ortholog of human SETD1A (SET domain containing 1A, histone lysine methyltransferase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070417 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29010) | ||||
| DOID:0070471 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29010) | ||||||
| Molecular_info | Corresponding_CDS | C26E6.9a | |||||||
| C26E6.9b | |||||||||
| C26E6.9c | |||||||||
| Corresponding_transcript | C26E6.9a.1 | ||||||||
| C26E6.9b.1 | |||||||||
| C26E6.9c.1 | |||||||||
| Other_sequence (35) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern (14) | |||||||||
| Drives_construct | WBCnstr00005981 | ||||||||
| WBCnstr00013270 | |||||||||
| WBCnstr00013628 | |||||||||
| WBCnstr00019766 | |||||||||
| WBCnstr00020418 | |||||||||
| WBCnstr00035390 | |||||||||
| WBCnstr00042038 | |||||||||
| Construct_product | WBCnstr00013270 | ||||||||
| WBCnstr00013628 | |||||||||
| WBCnstr00019766 | |||||||||
| WBCnstr00020473 | |||||||||
| WBCnstr00035390 | |||||||||
| Regulate_expr_cluster (12) | |||||||||
| Antibody | WBAntibody00000438 | ||||||||
| Microarray_results (39) | |||||||||
| Expression_cluster (151) | |||||||||
| Interaction (45) | |||||||||
| Map_info | Map | III | Position | -2.35202 | Error | 0.002862 | |||
| Positive | Positive_clone | C26E6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (65) | |||||||||
| Remark | Sequence connection from [Strome S], 02/06/13 krb. | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
