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WormBase Tree Display for Gene: WBGene00006435

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Name Class

WBGene00006435EvidenceCGC_data_submission
SMapS_parentSequenceF25G6
IdentityVersion2
NameCGC_namestdh-4
Sequence_nameF25G6.5
Molecular_nameF25G6.5a
F25G6.5a.1
CE47137
F25G6.5b
CE52769
F25G6.5b.1
Other_nametag-57Person_evidenceWBPerson201
CELE_F25G6.5Accession_evidenceNDBBX284605
Public_namestdh-4
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
227 Nov 2007 15:17:26WBPerson2970Name_changeCGC_namestdh-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classstdh
AlleleWBVar01031693
WBVar01499903
WBVar01031694
WBVar01031695
WBVar01031696
WBVar01031697
WBVar01031698
WBVar01031699
WBVar01031700
WBVar01031701
WBVar01031702
WBVar01031703
WBVar01031704
WBVar01031705
WBVar01031706
WBVar01031707
WBVar00091830
WBVar00213429
WBVar00213430
WBVar00213431
WBVar01500129
WBVar01499056
WBVar02136741
WBVar00464872
WBVar00464873
WBVar00464874
WBVar00464875
WBVar01499316
StrainWBStrain00002288
WBStrain00035663
RNASeq_FPKM (74)
GO_annotation00003241
00003242
00003243
00003244
00028932
00028933
Ortholog (67)
Paralog (38)
Structured_descriptionConcise_descriptionstdh-4 encodes a putative steroid dehydrogenase expressed in larval and adult pharynx; STDH-4 is orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767 and STDH-1/-3; STDH-4 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00006204
WBPaper00006525
WBPaper00031006
Curator_confirmedWBPerson567
Date_last_updated26 Nov 2007 00:00:00
Automated_descriptionPredicted to enable oxidoreductase activity. Predicted to be involved in fatty acid elongation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5212)
DOID:1923Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5212)
DOID:0112248Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5212)
Molecular_infoCorresponding_CDSF25G6.5a
F25G6.5b
Corresponding_CDS_historyF25G6.5:wp230
Corresponding_transcriptF25G6.5a.1
F25G6.5b.1
Other_sequence (11)
Associated_featureWBsf718354
WBsf1000690
WBsf1000691
WBsf1000692
WBsf1020052
Experimental_infoRNAi_resultWBRNAi00045527Inferred_automaticallyRNAi_primary
WBRNAi00013885Inferred_automaticallyRNAi_primary
Expr_patternChronogram1449
Chronogram1662
Expr5858
Expr1012380
Expr1149442
Expr2016959
Expr2035107
Drives_constructWBCnstr00002988
WBCnstr00004487
WBCnstr00037909
Construct_productWBCnstr00037909
Microarray_results (18)
Expression_cluster (40)
Interaction (90)
Map_infoMapVPosition1.4451Error0.002002
PositivePositive_cloneF25G6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4869
Pseudo_map_position
ReferenceWBPaper00018598
WBPaper00038491
WBPaper00042257
WBPaper00055090
RemarkGene name created from parsing 'genotype' field from CGC strain informationCGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene