WormBase Tree Display for Gene: WBGene00012857
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WBGene00012857 | SMap | S_parent | Sequence | CHROMOSOME_V | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | pbo-5 | Paper_evidence | WBPaper00031426 | |||||
Person_evidence | WBPerson655 | ||||||||
Sequence_name | Y44A6E.1 | ||||||||
Molecular_name | Y44A6E.1a | ||||||||
Y44A6E.1a.1 | |||||||||
CE32021 | |||||||||
Y44A6E.1b | |||||||||
CE37284 | |||||||||
Y44A6E.1b.1 | |||||||||
Other_name | lgc-2 | Paper_evidence | WBPaper00029376 | ||||||
Person_evidence | WBPerson1430 | ||||||||
CELE_Y44A6E.1 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | pbo-5 | ||||||||
DB_info | Database | AceView | gene | 5V387 | |||||
WormQTL | gene | WBGene00012857 | |||||||
WormFlux | gene | WBGene00012857 | |||||||
NDB | locus_tag | CELE_Y44A6E.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00012857|UniProtKB=G5ECT0 | |||||||
family | PTHR18945 | ||||||||
NCBI | gene | 189903 | |||||||
RefSeq | protein | NM_001029068.5 | |||||||
NM_001029069.7 | |||||||||
SwissProt | UniProtAcc | G5ECT0 | |||||||
UniProt_GCRP | UniProtAcc | G5ECT0 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 18 May 2007 16:58:23 | WBPerson2970 | Name_change | CGC_name | lgc-2 | ||||
3 | 01 Feb 2008 14:41:12 | WBPerson2970 | Event | Acquires_merge | WBGene00003944 | ||||
Name_change | CGC_name | pbo-5 | |||||||
Other_name | lgc-2 | ||||||||
Acquires_merge | WBGene00003944 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | pbo | ||||||||
Allele | WBVar00094987 | Inferred_automatically | From strain object: EG4 | ||||||
WBVar00090424 | |||||||||
WBVar00094994 | |||||||||
WBVar00090423 | |||||||||
WBVar00095000 | |||||||||
WBVar00094999 | |||||||||
WBVar00094993 | |||||||||
WBVar00094998 | |||||||||
WBVar00094989 | |||||||||
WBVar00242539 | |||||||||
WBVar00090425 | |||||||||
WBVar00242551 | |||||||||
WBVar00094997 | |||||||||
WBVar00094992 | |||||||||
WBVar00094995 | |||||||||
WBVar00242538 | |||||||||
WBVar00094990 | |||||||||
WBVar00094988 | |||||||||
WBVar00094996 | |||||||||
WBVar00095001 | |||||||||
WBVar01110473 | |||||||||
WBVar01110474 | |||||||||
WBVar01110475 | |||||||||
WBVar01110476 | |||||||||
WBVar01110477 | |||||||||
WBVar01110478 | |||||||||
WBVar01110479 | |||||||||
WBVar01110480 | |||||||||
WBVar01110481 | |||||||||
WBVar01897569 | |||||||||
WBVar01897570 | |||||||||
WBVar01498436 | |||||||||
WBVar00229364 | |||||||||
WBVar02138527 | |||||||||
WBVar01756995 | |||||||||
WBVar01756996 | |||||||||
WBVar01756997 | |||||||||
WBVar01756998 | |||||||||
WBVar01756999 | |||||||||
WBVar01757000 | |||||||||
WBVar02026551 | |||||||||
WBVar01757001 | |||||||||
WBVar02026552 | |||||||||
WBVar01829935 | |||||||||
WBVar01757002 | |||||||||
WBVar01829936 | |||||||||
WBVar01757003 | |||||||||
WBVar01757004 | |||||||||
WBVar01757005 | |||||||||
WBVar01941365 | |||||||||
WBVar01978840 | |||||||||
WBVar01757006 | |||||||||
WBVar01978841 | |||||||||
WBVar01757007 | |||||||||
WBVar01978842 | |||||||||
WBVar01978843 | |||||||||
WBVar01678832 | |||||||||
WBVar01878017 | |||||||||
WBVar01878018 | |||||||||
WBVar01878019 | |||||||||
WBVar01878020 | |||||||||
WBVar01878021 | |||||||||
WBVar01878022 | |||||||||
WBVar02063455 | |||||||||
WBVar01600079 | |||||||||
WBVar01600080 | |||||||||
WBVar01600081 | |||||||||
WBVar01600082 | |||||||||
WBVar00491507 | |||||||||
WBVar00247221 | |||||||||
WBVar00491508 | |||||||||
WBVar00491509 | |||||||||
WBVar00491510 | |||||||||
WBVar00491511 | |||||||||
WBVar00491512 | |||||||||
WBVar00491513 | |||||||||
WBVar00074047 | |||||||||
WBVar00074048 | |||||||||
WBVar00491514 | |||||||||
WBVar00491515 | |||||||||
WBVar00074049 | |||||||||
WBVar00074050 | |||||||||
WBVar00491516 | |||||||||
WBVar00074051 | |||||||||
WBVar00491517 | |||||||||
WBVar00491518 | |||||||||
WBVar01499446 | |||||||||
WBVar01926700 | |||||||||
WBVar02119252 | |||||||||
WBVar01497067 | |||||||||
WBVar01498729 | |||||||||
WBVar01526442 | |||||||||
WBVar01526443 | |||||||||
WBVar01526444 | |||||||||
WBVar01526445 | |||||||||
WBVar01498549 | |||||||||
WBVar01110447 | |||||||||
WBVar01110448 | |||||||||
WBVar01110449 | |||||||||
WBVar01110450 | |||||||||
WBVar01110451 | |||||||||
WBVar01110452 | |||||||||
WBVar01110453 | |||||||||
WBVar01110454 | |||||||||
WBVar01110455 | |||||||||
WBVar01110456 | |||||||||
WBVar01486066 | |||||||||
WBVar01110457 | |||||||||
WBVar01110458 | |||||||||
WBVar01110459 | |||||||||
WBVar02151042 | |||||||||
WBVar01110460 | |||||||||
WBVar01110461 | |||||||||
WBVar01110462 | |||||||||
WBVar01544424 | |||||||||
WBVar01110463 | |||||||||
WBVar01914172 | |||||||||
WBVar01110464 | |||||||||
WBVar01110465 | |||||||||
WBVar01110466 | |||||||||
WBVar01110467 | |||||||||
WBVar01110468 | |||||||||
WBVar01110469 | |||||||||
WBVar01110470 | |||||||||
WBVar01110471 | |||||||||
WBVar01110472 | |||||||||
Legacy_information | [C.elegansII] sa242 : pBoc step of defecation motor program completely absent, other aspects of motor program and timing normal; apparently normal feeding. NA1. [JT] | ||||||||
Strain | WBStrain00006657 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (18) | |||||||||
Ortholog (26) | |||||||||
Paralog (100) | |||||||||
Structured_description | Concise_description | pbo-5 encodes a proton-gated ion channel required for normal posterior body muscle contractions during defecation; PBO-5 has no obvious non-nematode orthologs, but is paralogous to PBO-6/LGC-3; PBO-5 is expressed in the most posterior bodywall muscles, and in the head neurons RIFL, RIFR, and RIS; heterologous PBO-5/PBO-6 produces strong currents in Xenopus oocytes when stimulated by pH 6.0; pbo-5 mutants are completely deficient in posterior contractions, but move normally, indicating that their defect is in defecation rather than in a more general one in posterior muscle function; pbo-5 mutants have normal PBO-4-mediated acidification pulses at the basolateral face of the posterior intestine, yet fail to contract. | Paper_evidence | WBPaper00001256 | |||||
WBPaper00031426 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 05 Feb 2008 00:00:00 | ||||||||
Automated_description | Enables extracellular ligand-gated monoatomic ion channel activity. Involved in defecation; lipid transport involved in lipid storage; and positive regulation of multicellular organismal process. Predicted to be located in neuron projection and synapse. Expressed in RIFL; RIFR; RIS; and body wall musculature. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | Y44A6E.1a | |||||||
Y44A6E.1b | |||||||||
Corresponding_CDS_history | Y44A6E.1:wp87 | ||||||||
Corresponding_transcript | Y44A6E.1a.1 | ||||||||
Y44A6E.1b.1 | |||||||||
Other_sequence | Tcol_isotig20449 | ||||||||
Oden_isotig15669 | |||||||||
Associated_feature | WBsf647774 | ||||||||
WBsf662288 | |||||||||
WBsf662289 | |||||||||
WBsf1003664 | |||||||||
WBsf1003665 | |||||||||
WBsf1003666 | |||||||||
WBsf1022027 | |||||||||
WBsf1022028 | |||||||||
WBsf1022029 | |||||||||
Experimental_info | RNAi_result | WBRNAi00066374 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00056554 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr9628 | ||||||||
Expr1012602 | |||||||||
Expr1160028 | |||||||||
Expr2014762 | |||||||||
Expr2032996 | |||||||||
Drives_construct | WBCnstr00014189 | ||||||||
Construct_product | WBCnstr00042604 | ||||||||
Microarray_results (24) | |||||||||
Expression_cluster (104) | |||||||||
Interaction | WBInteraction000554935 | ||||||||
WBInteraction000556792 | |||||||||
Map_info | Map | V | Position | 25.8116 | |||||
Positive | Positive_clone | Y44A6E | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (12) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |