WormBase Tree Display for Gene: WBGene00018678

WBGene00018678 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 2
    Name: CGC_name: tdpo-1 Person_evidence: WBPerson1720
            WBPerson195
      Sequence_name: F52C12.1
      Molecular_name: F52C12.1a
        F52C12.1a.1
        CE19434
        F52C12.1b
        CE48525
        F52C12.1c
        CE48982
        F52C12.1b.1
        F52C12.1c.1
      Other_name: CELE_F52C12.1 Accession_evidence: NDB BX284604
      Public_name: tdpo-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 04 Jul 2019 11:28:17 WBPerson1983 Name_change: CGC_name: tdpo-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tdpo
    Allele: WBVar00890075
      WBVar00890076
      WBVar02048175
      WBVar00890077
      WBVar00890078
      WBVar00890079
      WBVar00890080
      WBVar00890081
      WBVar00890082
      WBVar01821183
      WBVar01499166
      WBVar02110143
      WBVar02076422
      WBVar01511948
      WBVar01511949
      WBVar01894065
      WBVar01894066
      WBVar01894067
      WBVar02133396
      WBVar02133397
      WBVar00418437
      WBVar00418438
      WBVar00418439
      WBVar00418440
      WBVar00418441
      WBVar00418442
      WBVar00418443
      WBVar00418444
      WBVar00418445
      WBVar00418446
      WBVar00418447
      WBVar01609157
      WBVar02015296
      WBVar02041778
      WBVar01921442
      WBVar01921443
      WBVar01450996
      WBVar01450997
      WBVar01499633
      WBVar01964990
      WBVar01964991
      WBVar01964992
      WBVar01964993
      WBVar00184742
      WBVar00184743
      WBVar00184744
      WBVar00184745
      WBVar00184746
      WBVar01823519
      WBVar00569380
      WBVar01803257
      WBVar01823520
      WBVar01803258
      WBVar00569382
      WBVar01823521
      WBVar01823522
      WBVar01803259
      WBVar00569383
      WBVar01803260
      WBVar01823523
      WBVar01580039
      WBVar02049063
      WBVar01984901
      WBVar02008130
      WBVar02008131
      WBVar00258157
      WBVar02008132
      WBVar00890061
      WBVar00890062
      WBVar00890063
      WBVar00890064
      WBVar00890065
      WBVar00890066
      WBVar00890067
      WBVar01491596
      WBVar00890068
      WBVar00890069
      WBVar01500062
      WBVar00890070
      WBVar00890071
      WBVar01687819
      WBVar00890072
      WBVar00890073
      WBVar01687820
      WBVar00890074
    Strain: WBStrain00051054
    RNASeq_FPKM (74)
    GO_annotation (15)
    Contained_in_operon: CEOP4052
    Ortholog (34)
    Structured_description: Automated_description: Predicted to enable 3'-tyrosyl-DNA phosphodiesterase activity; double-stranded DNA binding activity; and single-stranded DNA binding activity. Predicted to be involved in DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 1 with axonal neuropathy. Is an ortholog of human TDP1 (tyrosyl-DNA phosphodiesterase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0090115 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18884)
  Molecular_info: Corresponding_CDS: F52C12.1a
      F52C12.1b
      F52C12.1c
    Corresponding_transcript: F52C12.1a.1
      F52C12.1b.1
      F52C12.1c.1
    Other_sequence: JI178755.1
      Hbac_isotig06861
      Dviv_isotig08196
      Dviv_isotig08200
      Dviv_isotig08199
      JI169950.1
      CBC07186_1
      Dviv_isotig08197
      CJC16761_1
      Oden_isotig23331
    Associated_feature: WBsf227988
  Experimental_info: RNAi_result: WBRNAi00007988 Inferred_automatically: RNAi_primary
      WBRNAi00032587 Inferred_automatically: RNAi_primary
      WBRNAi00015368 Inferred_automatically: RNAi_primary
      WBRNAi00047926 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1028560
      Expr1038039
      Expr1151755
      Expr2003975
      Expr2022196
    Microarray_results (23)
    Expression_cluster (113)
    Interaction (18)
  Map_info: Positive: Positive_clone: F52C12 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: IV -12.6559
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene