WormBase Tree Display for Gene: WBGene00021349
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| WBGene00021349 | SMap | S_parent | Sequence | Y37E3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | arl-13 | Person_evidence | WBPerson4071 | |||||
| Sequence_name | Y37E3.5 | ||||||||
| Molecular_name (13) | |||||||||
| Other_name | CELE_Y37E3.5 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | arl-13 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:04 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 20 Nov 2007 10:25:06 | WBPerson2970 | Name_change | CGC_name | arl-13 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | arl | ||||||||
| Allele | WBVar00617482 | ||||||||
| WBVar00617483 | |||||||||
| WBVar00617484 | |||||||||
| WBVar00617485 | |||||||||
| WBVar00617486 | |||||||||
| WBVar00617487 | |||||||||
| WBVar00617488 | |||||||||
| WBVar00617489 | |||||||||
| WBVar02011794 | |||||||||
| WBVar00025321 | |||||||||
| WBVar00149923 | |||||||||
| WBVar00149924 | |||||||||
| WBVar00149925 | |||||||||
| WBVar01499003 | |||||||||
| WBVar01325883 | |||||||||
| WBVar01531136 | |||||||||
| WBVar01499559 | |||||||||
| WBVar01556121 | |||||||||
| WBVar02001456 | |||||||||
| WBVar00251224 | |||||||||
| WBVar00145886 | |||||||||
| WBVar01788420 | |||||||||
| WBVar01497379 | |||||||||
| WBVar01573695 | |||||||||
| WBVar01573696 | |||||||||
| WBVar01573697 | |||||||||
| WBVar01662075 | |||||||||
| WBVar01662076 | |||||||||
| WBVar01662077 | |||||||||
| WBVar02070495 | |||||||||
| WBVar01662078 | |||||||||
| WBVar01712265 | |||||||||
| WBVar01712266 | |||||||||
| WBVar01499786 | |||||||||
| WBVar01694540 | |||||||||
| WBVar00250710 | |||||||||
| WBVar01416599 | |||||||||
| WBVar01499985 | |||||||||
| WBVar00327579 | |||||||||
| WBVar00327580 | |||||||||
| WBVar00327581 | |||||||||
| WBVar00327582 | |||||||||
| WBVar00327583 | |||||||||
| WBVar00327584 | |||||||||
| WBVar00327585 | |||||||||
| WBVar00534342 | |||||||||
| WBVar01416710 | |||||||||
| WBVar00617462 | |||||||||
| WBVar00617463 | |||||||||
| WBVar00617464 | |||||||||
| WBVar00617465 | |||||||||
| WBVar00617466 | |||||||||
| WBVar00617467 | |||||||||
| WBVar00617468 | |||||||||
| WBVar00617469 | |||||||||
| WBVar00617470 | |||||||||
| WBVar00617471 | |||||||||
| WBVar00617472 | |||||||||
| WBVar00617473 | |||||||||
| WBVar00617474 | |||||||||
| WBVar00617475 | |||||||||
| WBVar00617476 | |||||||||
| WBVar00617477 | |||||||||
| WBVar00617478 | |||||||||
| WBVar00617479 | |||||||||
| WBVar00617480 | |||||||||
| WBVar00617481 | |||||||||
| Strain | WBStrain00002472 | ||||||||
| WBStrain00036326 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (30) | |||||||||
| Ortholog (38) | |||||||||
| Paralog (14) | |||||||||
| Structured_description | Concise_description | arl-13 encodes the ortholog of human Arl13b which encodes the small ciliary G protein, adenosine diphosphate ribosylation factor-like protein; arl-13 is required for normal ciliary morphology and function and intraflagellar transport (IFT), arl-13 functions with the small GTPase, arl-3 for the stability of the IFT complex; arl-13 also interacts genetically with IFT-related genes like nphp-4, klp-11, bbs-8 and dyf-5 to maintain ciliary structure and anterograde IFT; ARL-13 is expressed in ciliated sensory neurons in the proximal ciliary regions and associates with the ciliary membrane via palmitoyl anchors. | Curator_confirmed | WBPerson324 | |||||
| Date_last_updated | 26 Jan 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTP binding activity and GTPase activity. Involved in cilium organization; receptor localization to non-motile cilium; and sensory perception of chemical stimulus. Acts upstream of or within motile cilium assembly. Located in plasma membrane bounded cell projection. Expressed in ciliated neurons and head. Used to study Joubert syndrome. Human ortholog(s) of this gene implicated in Joubert syndrome 8. Is an ortholog of human ARL13B (ADP ribosylation factor like GTPase 13B). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:0050777 | Homo sapiens | Paper_evidence | WBPaper00036031 | ||||
| WBPaper00036362 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson38202 | |||||||||
| Date_last_updated | 03 Jul 2018 00:00:00 | ||||||||
| Potential_model | DOID:0111003 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:25419) | |||||
| Models_disease_asserted | WBDOannot00000034 | ||||||||
| WBDOannot00000602 | |||||||||
| WBDOannot00000603 | |||||||||
| Molecular_info | Corresponding_CDS | Y37E3.5a | |||||||
| Y37E3.5b | |||||||||
| Y37E3.5c | |||||||||
| Y37E3.5d | |||||||||
| Corresponding_CDS_history | Y37E3.5:wp147 | ||||||||
| Corresponding_transcript | Y37E3.5a.1 | ||||||||
| Y37E3.5b.1 | |||||||||
| Y37E3.5c.1 | |||||||||
| Y37E3.5c.2 | |||||||||
| Y37E3.5d.1 | |||||||||
| Other_sequence | JI255318.1 | ||||||||
| Associated_feature | WBsf034252 | ||||||||
| WBsf047494 | |||||||||
| WBsf643078 | |||||||||
| WBsf982802 | |||||||||
| WBsf1009288 | |||||||||
| WBsf217272 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00055938 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern (15) | |||||||||
| Drives_construct (34) | |||||||||
| Construct_product (14) | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (130) | |||||||||
| Interaction (26) | |||||||||
| Map_info | Map | I | Position | -12.0683 | Error | 0.035686 | |||
| Positive | Positive_clone | Y37E3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (28) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
