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WormBase Tree Display for Gene: WBGene00022034

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Name Class

WBGene00022034SMapS_parentSequenceY65B4BL
IdentityVersion2
NameCGC_namedeps-1Person_evidenceWBPerson632
Sequence_nameY65B4BL.2
Molecular_nameY65B4BL.2a
Y65B4BL.2a.1
CE25536
Y65B4BL.2b
CE49430
Y65B4BL.2b.1
Other_nameCELE_Y65B4BL.2Accession_evidenceNDBBX284601
Public_namedeps-1
DB_infoDatabaseAceViewgene1A981
WormQTLgeneWBGene00022034
WormFluxgeneWBGene00022034
NDBlocus_tagCELE_Y65B4BL.2
NCBIgene171642
RefSeqproteinNM_058341.6
NM_001306264.3
SwissProtUniProtAccQ9N303
UniProt_GCRPUniProtAccQ9N303
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
210 May 2007 14:24:04WBPerson2970Name_changeCGC_namedeps-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdeps
AlleleWBVar00094560Inferred_automaticallyFrom strain object: RB2583
WBVar02141352
WBVar02141353
WBVar00532503
WBVar01284739
WBVar02125959
WBVar01403967
WBVar01992753
WBVar00607412
WBVar00607413
WBVar00607414
WBVar00607415
WBVar00607416
WBVar00607417
WBVar00607418
WBVar00607419
WBVar00607420
WBVar00000497
WBVar00607421
WBVar00607422
WBVar00607423
WBVar00000499
WBVar00607424
WBVar00000501
WBVar00000504
WBVar01499786
WBVar00255871
WBVar01499619
WBVar01429811
WBVar01417399
WBVar00147515
WBVar00324308
WBVar00324309
WBVar00324310
WBVar00324311
WBVar00324312
WBVar00324313
WBVar00324314
WBVar00324315
WBVar00324316
WBVar00324317
WBVar00324318
WBVar01640038
WBVar00324319
StrainWBStrain00033258
WBStrain00034459
WBStrain00005683
WBStrain00022452
RNASeq_FPKM (74)
GO_annotation00093439
00093440
00093441
00093442
Ortholog (25)
Structured_descriptionConcise_descriptiondeps-1 encodes an large (619-residue), unfamiliar P-granule-associated protein required for germline RNAi, PGL-1's localization in P granules, accumulation of GLH-1 and RDE-4 (along with glh-1 mRNA), germline proliferation and fertility at high temperatures, and embryonic viability at low temperatures; unless rescued by maternal DEPS-1, deps-1 mutants show temperature-sensitive sterility at 24+ deg. C., but remain fertile at 15-20 deg. C.; DEPS-1 upregulates 13 germline-expressed genes (including glh-1, rde-4, aco-2, cts-1, plk-3, and deps-1 itself), and downregulates 32 such genes (including dyf-3, klp-10, pvf-1, rnh-1.3, and ugt-64); DEPS-1 has a C-terminal serine-rich domain, and has orthologs in other Caenorhabditis species, but has no non-nematode orthologs.Paper_evidenceWBPaper00031477
Curator_confirmedWBPerson567
Date_last_updated15 Feb 2008 00:00:00
Automated_descriptionPredicted to be involved in regulatory ncRNA-mediated gene silencing. Located in P granule. Expressed in germ line and oocyte.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY65B4BL.2a
Y65B4BL.2b
Corresponding_transcriptY65B4BL.2a.1
Y65B4BL.2b.1
Other_sequenceTcir_isotig05964
CRC07188_1
CBC04710_1
CR07679
Associated_featureWBsf982516
WBsf982517
WBsf982518
WBsf217136
Experimental_infoRNAi_resultWBRNAi00026908Inferred_automaticallyRNAi_primary
WBRNAi00026909Inferred_automaticallyRNAi_primary
WBRNAi00057910Inferred_automaticallyRNAi_primary
WBRNAi00024249Inferred_automaticallyRNAi_primary
WBRNAi00004770Inferred_automaticallyRNAi_primary
WBRNAi00023372Inferred_automaticallyRNAi_primary
WBRNAi00023885Inferred_automaticallyRNAi_primary
WBRNAi00057905Inferred_automaticallyRNAi_primary
WBRNAi00024172Inferred_automaticallyRNAi_primary
WBRNAi00033344Inferred_automaticallyRNAi_primary
Expr_patternExpr7892
Expr1018173
Expr1039687
Expr1161339
Expr2010859
Expr2029097
Regulate_expr_clusterWBPaper00031477:Down_deps-1_vs_WT
WBPaper00031477:Up_deps-1_vs_WT
WBPaper00062123:DEPS-1_interacting
AntibodyWBAntibody00001372
Microarray_results (19)
Expression_cluster (181)
Interaction (156)
Map_infoMapIPosition-18.9833Error0.006079
PositivePositive_cloneY65B4BLInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027804
WBPaper00031477
WBPaper00035324
WBPaper00043989
WBPaper00052166
WBPaper00057161
WBPaper00059254
WBPaper00060139
WBPaper00063892
WBPaper00064472
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene