WBGene00001085 | SMap | S_parent | Sequence | C25G4 |
| Identity | Version | 1 |
| | Name | CGC_name | dpy-26 | Person_evidence | WBPerson261 |
| | | Sequence_name | C25G4.5 |
| | | Molecular_name | C25G4.5 |
| | | | C25G4.5.1 |
| | | | CE08398 |
| | | Other_name | CELE_C25G4.5 | Accession_evidence | NDB | BX284604 |
| | | Public_name | dpy-26 |
| | DB_info | Database (9) |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | dpy |
| | Reference_allele | WBVar00089317 |
| | Allele (97) |
| | Legacy_information | n199mat : XX daughters of n199/+ mothers are maternally rescued weak dumpy phenotype with protruding vulva (ES2) 4% Him; XX daughters of n199/n199 mothers are severely dumpy and Him (2% of brood) or die as embryos or young larvae (98% of XX brood). XO n199 animals are non-dumpy almost wildtype males (ME3). Similar or slightly stronger phenotypes in n199/Df. NA3 (n198 (resembles n199) y6 (weaker phenotypes). |
| | | See also n198, n199, y6 |
| | | [C.elegansII] n199mat : XX daughters of n199/+ mothers are maternally rescued weak dumpy phenotype with protruding vulva (ES2) 4% Him; XX daughters of n199/n199 mothers are severely dumpy and Him (2% of brood) or die as embryos or young larvae (98% of XX brood). XO n199 animals are non-dumpy almost wildtype males (ME3). Similar or slightly stronger phenotypes in n199/Df. OA3: n198 (resembles n199), y6 (weaker phenotypes), y65. Cloned: encodes predicted 1263 aa novel protein; antibody staining indicates DPY-26 associated with X chromosomes in XX, diffuse nuclear in XO. [Plenefisch et al. 1989; TY] |
| | Strain | WBStrain00004455 |
| | | WBStrain00004613 |
| | | WBStrain00004619 |
| | | WBStrain00004623 |
| | | WBStrain00034748 |
| | | WBStrain00054695 |
| | RNASeq_FPKM (74) |
| | GO_annotation (15) |
| | Contained_in_operon | CEOP4516 |
| | Ortholog (18) |
| | Structured_description | Concise_description | dpy-26 encodes a novel, acidic protein that is highly conserved in other Caenorhabditis species; during development, dpy-26 activity is required for both dosage compensation and meiotic chromosome segregation; DPY-26 localizes to all meiotic chromosomes in the germline and to the hermaphrodite X chromosomes in somatic cells; SDC-1, SDC-2, and SDC-3 proteins form a complex and these three proteins, in turn, colocalize with DPY-26, DPY-27, and MIX-1 proteins both on the X chromosome and on a transgenic her-1(+) array. | Paper_evidence | WBPaper00002605 |
| | | | | | WBPaper00002606 |
| | | | | | WBPaper00005215 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | | WBPerson567 |
| | | | | Date_last_updated | 21 May 2007 00:00:00 |
| | | Automated_description | Involved in dosage compensation by hypoactivation of X chromosome; meiotic sister chromatid segregation; and mitotic sister chromatid segregation. Located in condensed nuclear chromosome. Part of dosage compensation complex. Expressed widely. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | C25G4.5 |
| | Corresponding_transcript | C25G4.5.1 |
| | Other_sequence | U43562 |
| | | CBC04037_1 |
| | | CR05839 |
| | | CRC11903_1 |
| | | PPC12755_1 |
| | | CBC13777_1 |
| | | CBC01161_1 |
| | | CRC07128_1 |
| | Associated_feature | WBsf652298 |
| | | WBsf668431 |
| | | WBsf231021 |
| | | WBsf231022 |
| | | WBsf231023 |
| Experimental_info | RNAi_result | WBRNAi00041214 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00011181 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00080293 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00080269 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00080286 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00080273 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00080282 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr1570 |
| | | Expr9851 |
| | | Expr1022687 |
| | | Expr1030690 |
| | | Expr1145250 |
| | | Expr1200198 |
| | | Expr2011067 |
| | | Expr2029304 |
| | Drives_construct | WBCnstr00037090 |
| | Construct_product | WBCnstr00037090 |
| | Antibody | WBAntibody00000131 |
| | | WBAntibody00000807 |
| | | WBAntibody00000808 |
| | | WBAntibody00001591 |
| | | WBAntibody00001964 |
| | | WBAntibody00002034 |
| | | WBAntibody00002040 |
| | | WBAntibody00002734 |
| | Microarray_results (23) |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_downregulated |
| | | WBPaper00037950:A-class-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:all-neurons_L1-larva_expressed |
| | | WBPaper00037950:all-neurons_L2-larva_expressed |
| | | WBPaper00037950:AVA-neuron_L1-larva_expressed |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:bodywall-muscle_L2-larva_expressed |
| | | WBPaper00037950:coelomocytes_L2-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00044426:rotenone_24h_downregulated |
| | | WBPaper00044656:tatn-1(qd182)_downregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044760:germline_specific |
| | | WBPaper00045420:fertilization_downregulated_transcript |
| | | WBPaper00045521:Gender_Neutral |
| | | WBPaper00045571:germline-ablation_downregulated |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049159:Microwave_upregulated_adult |
| | | WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031) |
| | | WBPaper00049920:Glucose-Diet_downregulated_N2 |
| | | WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi) |
| | | WBPaper00049942:hsf-1(RNAi)_upregulated |
| | | WBPaper00050344:AFD-neuron_enriched |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051265:F4_morc-1(tm6048)_upregulated |
| | | WBPaper00052884:emb-4(hc60)_downregulated |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053302:alovudine_24h_regulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00055060:flr-1(RNAi)_upregulated |
| | | WBPaper00055226:ADR-2_target_N2 |
| | | WBPaper00055334:DLC-1_interacting |
| | | WBPaper00055354:Psora-Allantoin_upregulated |
| | | WBPaper00055354:Rapamycin-Metformin_upregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00055862:antimycin_damt-1(gk961032)_regulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_upregulated |
| | | WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047) |
| | | WBPaper00057288:Cold_downregulated_transcript |
| | | WBPaper00058691:cfp-1(tm6369)_downregulated |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00059664:srbc-48(ac23)_downregulated |
| | | WBPaper00060445:nfki-1(cer1)_upregulated_L4 |
| | | WBPaper00060683:hlh-11(ko1)_downregulated |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00061274:microgravity_upregulated |
| | | WBPaper00061340:ADL_parent |
| | | WBPaper00061340:PLM_ALN_grandparent |
| | | WBPaper00061439:unc-30(ok613)_downregulated |
| | | WBPaper00061479:HDA-1_interacting_protein |
| | | WBPaper00061527:dpy-26-B0205.1 |
| | | WBPaper00062159:hda-2(ok1479)_downregulated |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00062456:doxycycline_downregulated_CB4856_protein |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064716:paraquat_upregulated |
| | | WBPaper00065096:Day10_vs_Day1_upregulated |
| | | WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected |
| | | WBPaper00065373:sek-1(km4)_upregulated_cisplatin |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066110:tetraploid_vs_diploid_downregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14 |
| | | cgc4386_cluster_6_1 |
| | | WBPaper00024671:AFD_AWB_vs_unsorted_upregulated |
| | | WBPaper00025032:cluster_7 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00032165:differentially_expressed_with_age_medoid_1 |
| | | WBPaper00035905:FBF-1_Associated |
| | | WBPaper00036123:Fluoranthene_regulated |
| | | WBPaper00036286:Pattern_B |
| | | WBPaper00038060:SUMO-1_upregulated |
| | | WBPaper00040823:alg-1(gk214)_downregulated |
| | | WBPaper00041002:HF_3d_2.0mM_Down |
| | | WBPaper00041606:CE_B.thuringiensis-DB27_regulated |
| | | WBPaper00041606:CE_S.marcescens_regulated |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00042258:DA1877_downregulated_GravidAdult |
| | | WBPaper00048989:N2_rapamycin_downregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | WBPaper00057098:SiO2-nanoparticles_upregulated |
| | | [cgc5767]:cluster_4 |
| | | [cgc5767]:expression_class_E |
| | | [cgc5767]:expression_class_E_pi(23_min) |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_ME |
| | | [cgc6390]:Cluster_F |
| | | [cgc6390]:intrinsic |
| | Interaction (86) |
| | WBProcess | WBbiopr:00000056 |
| | | WBbiopr:00000099 |
| Map_info | Map | IV | Position | 5.94177 | Error | 0.00601 |
| | Well_ordered |
| | Positive | Positive_clone | C25G4 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | 2_point | 648 |
| | | | 819 |
| | | | 823 |
| | | | 824 |
| | | Multi_point | 568 |
| | | | 569 |
| | | | 570 |
| | | | 764 |
| | | | 765 |
| | | | 766 |
| | | | 767 |
| | | | 1916 |
| | | | 5281 |
| | Landmark_gene |
| Reference (112) |
| Method | Gene |