WormBase Tree Display for Gene: WBGene00001172

WBGene00001172 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: C51E3
  Identity: Version: 1
    Name: CGC_name: egl-3 Person_evidence: WBPerson268
      Sequence_name: C51E3.7
      Molecular_name: C51E3.7a
        C51E3.7a.1
        CE08940
        C51E3.7c
        CE45708
        C51E3.7c.1
      Other_name: kpc-2
        pc2 Accession_evidence: EMBL U04995
        CELE_C51E3.7 Accession_evidence: NDB BX284605
      Public_name: egl-3
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:23 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info (12)
  Disease_info: Experimental_model: DOID:1574 Homo sapiens Paper_evidence: WBPaper00036327
          Curator_confirmed: WBPerson324
          Date_last_updated: 06 Jun 2019 00:00:00
    Potential_model: DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8744)
      DOID:5844 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8744)
  Models_disease_asserted: WBDOannot00000710
  Molecular_info: Corresponding_CDS: C51E3.7a
      C51E3.7c
    Corresponding_CDS_history: C51E3.7b:wp261
    Corresponding_transcript: C51E3.7a.1
      C51E3.7c.1
    Other_sequence (127)
    Associated_feature (12)
  Experimental_info: RNAi_result (29)
    Expr_pattern (15)
    Drives_construct: WBCnstr00002351
      WBCnstr00004319
      WBCnstr00008114
      WBCnstr00018293
      WBCnstr00020688
      WBCnstr00037050
    Construct_product: WBCnstr00011520
      WBCnstr00017600
      WBCnstr00017601
      WBCnstr00021861
      WBCnstr00037050
    Antibody: WBAntibody00000429
    Microarray_results (30)
    Expression_cluster: WBPaper00024970:GABAergic_neuron_specific
      WBPaper00029359_1166
      WBPaper00029359_1194
      WBPaper00029359_1197
      WBPaper00029359_1240
      WBPaper00029359_1243
      WBPaper00029359_1291
      WBPaper00029359_1336
      WBPaper00029359_1546
      WBPaper00029359_1549
      WBPaper00029359_1557
      WBPaper00029359_1599
      WBPaper00030922:glycosylated_protein
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035211:age-1_vs_N2_downregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:A-class-motor-neurons_larva_enriched
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:BAG-neuron_embryo_enriched
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044656:tatn-1(qd182)_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044743:wdr-23_neuron_upregulated
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045521:Gender_Neutral
      WBPaper00045861:ash-2(tm1095)_upregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046858:elt-2(RNAi)_downregulated
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049001:EVN_enriched
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050015:ifg-1(RNAi)_upregulated
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00052987:UV_upregulated_xpc-1;csb-1
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(icb38)_upregulated
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:nerve-ring_expressed
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_enriched
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059203:CAR-1_interacting
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059471:EGL-43_interacting
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059987:Wounding_upregulated
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AFD
      WBPaper00061340:AIA
      WBPaper00061340:AIB
      WBPaper00061340:AIN
      WBPaper00061340:AIY
      WBPaper00061340:AVD
      WBPaper00061340:AVK
      WBPaper00061340:AVL
      WBPaper00061340:AWC
      WBPaper00061340:PVT
      WBPaper00061340:RIM
      WBPaper00061340:RIS
      WBPaper00061340:SIA
      WBPaper00061340:Z1_Z4
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:flp-5-F17C11.2
      WBPaper00061527:snt-4_17845-T27C4.1
      WBPaper00061651:ADA_enriched
      WBPaper00061651:AIA_enriched
      WBPaper00061651:AIB_enriched
      WBPaper00061651:AIM_enriched
      WBPaper00061651:AIN_enriched
      WBPaper00061651:AIY_enriched
      WBPaper00061651:AIZ_enriched
      WBPaper00061651:ALA_enriched
      WBPaper00061651:AVA_enriched
      WBPaper00061651:AVF_enriched
      WBPaper00061651:AVK_enriched
      WBPaper00061651:AVL_enriched
      WBPaper00061651:AVM_enriched
      WBPaper00061651:BAG_enriched
      WBPaper00061651:BDU_enriched
      WBPaper00061651:DVA_enriched
      WBPaper00061651:DVB_enriched
      WBPaper00061651:DVC_enriched
      WBPaper00061651:HSN_enriched
      WBPaper00061651:I5_enriched
      WBPaper00061651:IL2_LR_enriched
      WBPaper00061651:M1_enriched
      WBPaper00061651:MI_enriched
      WBPaper00061651:PDA_enriched
      WBPaper00061651:PVR_enriched
      WBPaper00061651:PVT_enriched
      WBPaper00061651:RIB_enriched
      WBPaper00061651:RID_enriched
      WBPaper00061651:RIF_enriched
      WBPaper00061651:RIG_enriched
      WBPaper00061651:RIH_enriched
      WBPaper00061651:RIR_enriched
      WBPaper00061651:RIS_enriched
      WBPaper00061651:RIV_enriched
      WBPaper00061651:RMG_enriched
      WBPaper00061651:RMH_enriched
      WBPaper00061651:SDQ_enriched
      WBPaper00061651:URB_enriched
      WBPaper00061651:URX_enriched
      WBPaper00061651:VC_4_5_enriched
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062103:neuron_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062520:qui-1(db104)_upregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064716:paraquat_downregulated
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00064871:hypoxia_downregulated_F2
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_enriched
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065623:94
      WBPaper00065623:100
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065841:68_0
      WBPaper00065841:68_1
      WBPaper00065841:74_0
      WBPaper00065841:92_0
      WBPaper00065841:97_0
      WBPaper00065841:103_0
      WBPaper00065841:104_0
      WBPaper00065841:105_0
      WBPaper00065841:107_0
      WBPaper00065841:112_0
      WBPaper00065841:121_0
      WBPaper00065841:122_0
      WBPaper00065841:123_0
      WBPaper00065841:128_0
      WBPaper00065841:129_0
      WBPaper00065841:134_0
      WBPaper00065841:144_0
      WBPaper00065841:145_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4489_group_14
      WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00027342:alpha-Synuclein(A53T)_downregulated
      WBPaper00028474:dys-1_downregulated
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00030839:Larval_A_Class
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00030985:Erwinia_carotovora_upregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00032948:StarveUp3
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035227:heat_shock_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-7_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00038060:SUMO-1_downregulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040821:Au-NP_regulated
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_prime
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042548:miRISC_enriched
      WBPaper00045865:biofilm_downregulated_B
      WBPaper00045865:biofilm_upregulated_A
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
    Interaction (98)
    Anatomy_function: WBbtf0062
      WBbtf0209
      WBbtf0210
      WBbtf1042
  Map_info: Map: V Position: 2.28568 Error: 0.005714
    Well_ordered
    Positive: Inside_rearr: mDf1
      Positive_clone: C51E3 Person_evidence: WBPerson1139
          Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 715
      Multi_point: 329
        608
        609
        797
        953
        5581
      Pos_neg_data: 1732
        1733
        1734
        1741
  Reference: WBPaper00000635
    WBPaper00001416
    WBPaper00001738
    WBPaper00001978
    WBPaper00004142
    WBPaper00004433
    WBPaper00004977
    WBPaper00005622
    WBPaper00005666
    WBPaper00005687
    WBPaper00005776
    WBPaper00006069
    WBPaper00006103
    WBPaper00010455
    WBPaper00010766
    WBPaper00010805
    WBPaper00010811
    WBPaper00013484
    WBPaper00014079
    WBPaper00016383
    WBPaper00016877
    WBPaper00017781
    WBPaper00018607
    WBPaper00023293
    WBPaper00025372
    WBPaper00026643
    WBPaper00026667
    WBPaper00026941
    WBPaper00027274
    WBPaper00028078
    WBPaper00028091
    WBPaper00028122
    WBPaper00028453
    WBPaper00028820
    WBPaper00028958
    WBPaper00028963
    WBPaper00029013
    WBPaper00029060
    WBPaper00030226
    WBPaper00030382
    WBPaper00030763
    WBPaper00030837
    WBPaper00031217
    WBPaper00031564
    WBPaper00031936
    WBPaper00032221
    WBPaper00032389
    WBPaper00034200
    WBPaper00035230
    WBPaper00035257
    WBPaper00035336
    WBPaper00035338
    WBPaper00035383
    WBPaper00036237
    WBPaper00036554
    WBPaper00038491
    WBPaper00039159
    WBPaper00039268
    WBPaper00039411
    WBPaper00040694
    WBPaper00042376
    WBPaper00042400
    WBPaper00042790
    WBPaper00043437
    WBPaper00043467
    WBPaper00043503
    WBPaper00044407
    WBPaper00045044
    WBPaper00045066
    WBPaper00046959
    WBPaper00047526
    WBPaper00047901
    WBPaper00047943
    WBPaper00048845
    WBPaper00050593
    WBPaper00053454
    WBPaper00055090
    WBPaper00055268
    WBPaper00055757
    WBPaper00056066
    WBPaper00058264
    WBPaper00058720
    WBPaper00061309
    WBPaper00061871
    WBPaper00061890
    WBPaper00062132
    WBPaper00062494
    WBPaper00062568
    WBPaper00063567
    WBPaper00063694
    WBPaper00063926
    WBPaper00064204
    WBPaper00064255
    WBPaper00064326
    WBPaper00064634
    WBPaper00064765
    WBPaper00064960
    WBPaper00065084
    WBPaper00065392
    WBPaper00065565
    WBPaper00065570
    WBPaper00065757
  Remark: sequence connection from [Kass J, Kaplan JM]
    Sequence connection from [Thacker C]
    old_name kpc-2 becomes new_name egl-3 from [Thacker C].
  Method: Gene