WormBase Tree Display for Gene: WBGene00003107

WBGene00003107 SMap: S_parent: Sequence: R166
  Identity: Version: 2
    Name: CGC_name: mab-10 Person_evidence: WBPerson3439
            WBPerson268
            WBPerson261
      Sequence_name: R166.1
      Molecular_name: R166.1a
        R166.1a.1
        CE43283
        R166.1a.2
        R166.1b
      Other_name: CELE_R166.1 Accession_evidence: NDB BX284602
      Public_name: mab-10
    DB_info: Database: AceView gene 2K821
        WormQTL gene WBGene00003107
        WormFlux gene WBGene00003107
        NDB locus_tag CELE_R166.1
        Panther gene CAEEL|WormBase=WBGene00003107|UniProtKB=Q22002
          family PTHR12623
        NCBI gene 187916
        RefSeq protein NM_063867.3
            NR_138506.1
        SwissProt UniProtAcc Q22002
        UniProt_GCRP UniProtAcc Q22002
        RNAcentral URSid URS0000A72B60
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:30 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 16 Jul 2007 08:40:06 WBPerson2970 Event: Acquires_merge: WBGene00011301
      Acquires_merge: WBGene00011301
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mab
    Reference_allele: WBVar00143858
    Allele (119)
    Legacy_information: e1248 : adult male has slightly swollen bursa reduced fan thin rays; some adult males have supernumerary molt. ES2 ME0. Hermaphrodite has slightly protruding vulva ES2. NA1.
      See also e1235, e1248
      [C.elegansII] e1248 : adult male has slightly swollen bursa, reduced fan, thin rays; some adult males have supernumerary molt, second adult cuticle. e1248/Df more severe. ES2 ME0. Hermaphrodite has slightly protruding vulva. ES2. NA1. [Hodgkin 1983a; Link et al. 1988; CB; CL]
    Strain: WBStrain00004492
    RNASeq_FPKM (74)
    GO_annotation (18)
    Ortholog (38)
    Structured_description: Automated_description: Enables DNA-binding transcription factor binding activity and transcription coregulator activity. Involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. Located in nucleus. Expressed in several structures, including gonad; hypodermis; pharynx; somatic nervous system; and vulval cell. Is an ortholog of human NAB1 (NGFI-A binding protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: R166.1a
    Corresponding_transcript: R166.1b
      R166.1a.1
      R166.1a.2
    Other_sequence: FC820380.1
      SRC05945_1
      FC819997.1
      JI167243.1
      JI469571.1
      ACC10272_1
      SR03237
      EX550854.1
    Associated_feature: WBsf989371
      WBsf989372
      WBsf989373
      WBsf989374
      WBsf989375
      WBsf1013034
      WBsf1013035
      WBsf1013036
      WBsf1013037
      WBsf1013038
  Experimental_info: RNAi_result: WBRNAi00017883 Inferred_automatically: RNAi_primary
      WBRNAi00034946 Inferred_automatically: RNAi_primary
      WBRNAi00051997 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr9660
      Expr9661
      Expr14647
      Expr1014146
      Expr1031469
      Expr1155639
      Expr2013322
      Expr2031554
    Drives_construct: WBCnstr00009532
      WBCnstr00014208
      WBCnstr00016068
      WBCnstr00036226
    Construct_product: WBCnstr00009532
      WBCnstr00014208
      WBCnstr00016068
      WBCnstr00036226
    Microarray_results (20)
    Expression_cluster: WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040560:hpl-2_embryo_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Oogenic
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00045974:NSM_enriched_totalRNA_tiling
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046805:csr-1(RNAi)_downregulated_Set1
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050717:let-7(n2853)_lin-41(xe11)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00054410:set-26(tm2467)_downregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055013:spt-16(RNAi)_downregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056169:rrf-3(pk1426)_downregulated_embryo
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056169:rrf-3(pk1426)_upregulated_L2
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056330:glycine_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-1(or286)_downregulated
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058945:mir-1(gk276)_upregulated
      WBPaper00059191:hsp-16.2p-LIN-29_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059471:EGL-43_interacting
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061040:FW1256_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:C36C5.12-F57G8.7
      WBPaper00061800:miR-85(n4117)_downregulated_20C
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064532:pals-25(icb98)_downregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4489_group_8
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:Resveratrol_regulated_N2
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00036286:Pattern_G
      WBPaper00037113:Diazinon_16C_regulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040985:AIN-2_asynchronous_intestine
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00045960:L1-L4-lethargus_downregulated
      WBPaper00045960:L4-lethargus_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (18)
  Map_info: Map: II Position: 3.07397 Error: 0.020491
    Positive: Positive_clone: R166 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 1392
        1393
        1394
        1395
      Pos_neg_data: 3356
        3671
        3674
        3788
        3789
        3790
  Reference: WBPaper00000608
    WBPaper00001057
    WBPaper00014014
    WBPaper00014527
    WBPaper00027910
    WBPaper00030578
    WBPaper00032662
    WBPaper00033681
    WBPaper00038491
    WBPaper00040121
    WBPaper00043697
    WBPaper00050717
    WBPaper00053906
    WBPaper00055090
    WBPaper00056453
    WBPaper00057618
    WBPaper00059191
    WBPaper00065308
    WBPaper00066105
  Method: Gene