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WormBase Tree Display for Gene: WBGene00000164

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Name Class

WBGene00000164SMapS_parentSequenceF53H8
IdentityVersion2
NameCGC_nameapm-3Person_evidenceWBPerson360
WBPerson567
Sequence_nameF53H8.1
Molecular_nameF53H8.1
F53H8.1.1
CE35723
Other_nameapt-7Person_evidenceWBPerson625
CELE_F53H8.1Accession_evidenceNDBBX284606
Public_nameapm-3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
201 Apr 2005 11:05:24WBPerson2970Name_changeCGC_nameapm-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classapm
Allele (34)
StrainWBStrain00003476
RNASeq_FPKM (74)
GO_annotation (11)
Contained_in_operonCEOPX012
Ortholog (38)
ParalogWBGene00000150Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001082Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00006777Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00006829Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionapm-3 encodes an adaptin, orthologous to the mu3 subunit of adaptor protein complex 3 (AP-3); APM-3 is also orthologous to human HPS, which when mutated leads to Hermansky-Pudlak syndrome (OMIM:203300); based on structural similarity, APM-3 is predicted to be involved in the formation of intracellular transport vesicles, and genetic analyses indicate that apm-3 activity is required for biogenesis of lysosome-related gut granules.Paper_evidenceWBPaper00004103
WBPaper00004907
WBPaper00005520
WBPaper00013041
WBPaper00025094
Curator_confirmedWBPerson1843
WBPerson324
WBPerson567
Date_last_updated23 Jan 2007 00:00:00
Automated_descriptionInvolved in lipid storage and lysosome organization. Predicted to be located in cytoplasmic vesicle. Predicted to be part of clathrin adaptor complex. Expressed in muscle cell; pharynx; spermatheca; and vulva. Is an ortholog of human AP3M1 (adaptor related protein complex 3 subunit mu 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF53H8.1
Corresponding_CDS_historyF53H8.1:wp108
Corresponding_transcriptF53H8.1.1
Other_sequence (63)
Associated_featureWBsf647808
WBsf662451
WBsf1003904
WBsf1022191
WBsf235299
Experimental_infoRNAi_result (11)
Expr_patternExpr3688
Expr6161
Expr12910
Expr1024542
Expr1030093
Expr1152010
Expr2009362
Expr2027598
Drives_constructWBCnstr00003937
WBCnstr00011600
WBCnstr00037694
Construct_productWBCnstr00022947
WBCnstr00023054
WBCnstr00037694
Microarray_results (22)
Expression_clusterWBPaper00032976:non_compensated_genes
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00044316:CH3HgCl_7.5uM_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Oogenic
WBPaper00045571:germline-ablation_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_enriched
WBPaper00048988:neuron_expressed
WBPaper00049498:npr-1(ur89)_regulated_3
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050094:glp-1(gf)_upregulated
WBPaper00050094:mes-2(bn11)_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050496:unc-39(hp701)_regulated
WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:intestine_expressed
WBPaper00051039:germline_enriched
WBPaper00051265:F4_hrde-1(tm1200)_upregulated
WBPaper00051265:F4_morc-1(tm6048)_upregulated
WBPaper00051558:aging_regulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053302:alovudine_72h_regulated
WBPaper00053321:mes-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:mes-4(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_embryo_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053599:female_vs_male_upregulated
WBPaper00053599:mitosis_vs_meiosis_downregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00055565:AVK_enriched
WBPaper00055827:daf-2(e1370)_upregulated
WBPaper00056039:ptl-1(ok621)_upregulated
WBPaper00056139:soil-microbiota_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056619:CEPsh_enriched
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00059027:neuron-synapses_depleted
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059471:EGL-43_interacting
WBPaper00059567:olrn-1(ums9)_regulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061340:AVH_parent
WBPaper00061340:CAN
WBPaper00061340:DA
WBPaper00061340:DB
WBPaper00061340:Neuroblast_AFD_RMD
WBPaper00061340:Neuroblast_AIZ_FLP_RMG
WBPaper00061340:SIB
WBPaper00061527:uggt-1_21889-tag-320_20312
WBPaper00061651:AVL_enriched
WBPaper00061651:DVB_enriched
WBPaper00061651:PDB_enriched
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062193:hsf-1(RNAi)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00064315:mes-3(bn199)_upregulated_EGCs
WBPaper00064315:mes-3(bn199)_upregulated_PGCs
WBPaper00064315:mes-4(bn73)_upregulated_EGCs
WBPaper00064315:mes-4(bn73)_upregulated_PGCs
WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
WBPaper00064769:him-17(me24)_downregulated
WBPaper00065158:25C_vs_15C_upregulated_AFD
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065841:68_1
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00066085:hda-3(ok1991)_upregulated
cgc4489_group_4
WBPaper00025032:cluster_7
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00028483:Up_mes-4_vs_WT
WBPaper00032165:differentially_expressed_with_age_medoid_1
WBPaper00035084:L1_enriched_AIN-2_IP
WBPaper00035084:L2_enriched_AIN-2_IP
WBPaper00035084:L3_enriched_AIN-2_IP
WBPaper00035084:L4_enriched_AIN-2_IP
WBPaper00035588:alg-1(-)_upregulated
WBPaper00038172:tax-6null_down_regulated
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00040963:TA200_down
WBPaper00040963:TA300_down
WBPaper00041002:HF_3d_2.0mM_Up
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045263:isp-1(qm150)_upregulated
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00045263:ProLongevity-mtROS_upregulated
WBPaper00045960:L1-L4-lethargus_downregulated
WBPaper00045960:L4-lethargus_downregulated
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:cluster_4
[cgc5767]:expression_class_E
[cgc5767]:expression_class_ET
[cgc5767]:expression_class_ET_max(101_min)
[cgc5767]:expression_class_E_pi(23_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
[cgc5767]:expression_class_MET
[cgc6390]:herm_sex-enriched
Interaction (27)
Map_infoMapXPosition-18.8908Error0.004786
PositivePositive_cloneF53H8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4163
4512
Pseudo_map_position
Reference (18)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene