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WormBase Tree Display for Gene: WBGene00000437

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Name Class

WBGene00000437SMapS_parentSequenceR13A5
IdentityVersion1
NameCGC_nameceh-13Person_evidenceWBPerson83
Sequence_nameR13A5.5
Molecular_nameR13A5.5
R13A5.5.1
CE28767
Other_nameCELE_R13A5.5Accession_evidenceNDBBX284603
Public_nameceh-13
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classceh
Allele (31)
Legacy_information[C.elegansII] pk20, pk36 : Tc1 insertions, no known phenotype. Encodes labial-like homeoprotein (68% identity in homeodomain). [Schaller et al. 1990]
StrainWBStrain00007522
WBStrain00035370
WBStrain00035371
WBStrain00035372
WBStrain00035830
WBStrain00007523
WBStrain00055067
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (41)
Paralog (14)
Structured_descriptionConcise_descriptiona homolog of Hox genes of labial/Hox1 type; affects viability, body shape and anterior patterning during embryogenesis, interacts genetically with hox genes; and is expressed in A, D, E and MS lineages in the early embryo, and in the anterior dorsal hypodermal cells, anterior body wall muscle cells, and in the cells of the prospective ventral nerve cord at the comma stage; and in the ventral nerve cord and and ventral and dorsal hypodermal cells in L1 larvae.Paper_evidenceWBPaper00002941
WBPaper00003508
WBPaper00017634
Curator_confirmedWBPerson480
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity. Involved in cell-cell adhesion and embryo development. Located in cytoplasm and nucleus. Expressed in several structures, including embryonic cell; hypodermis; neurons; non-striated muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in Athabaskan brainstem dysgenesis syndrome and autistic disorder. Is an ortholog of human HOXB1 (homeobox B1) and HOXD1 (homeobox D1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelEFO:MONDO:0011090Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5111)
DOID:0050682Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5099)
DOID:12849Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5099)
DOID:0060041Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5099)
Molecular_infoCorresponding_CDSR13A5.5
Corresponding_transcriptR13A5.5.1
Other_sequence (19)
Associated_feature (36)
Gene_product_bindsWBsf919530
Transcription_factorWBTranscriptionFactor000611
Experimental_infoRNAi_result (41)
Expr_pattern (38)
Drives_construct (13)
Construct_product (23)
AntibodyWBAntibody00000220
WBAntibody00000625
Microarray_results (20)
Expression_clusterWBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:A-class-motor-neurons_larva_enriched
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_CoreEnriched
WBPaper00037950:GABAergic-motor-neurons_embryo_enriched
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_larva_enriched
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:hypodermis_larva_enriched
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00041222:unc-120(st364)_downregulated
WBPaper00044316:CH3HgCl_7.5uM_downregulated
WBPaper00044656:tatn-1(qd182)_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045729:gld-2(RNAi)_downregulated
WBPaper00045774:clk-1_downregulated
WBPaper00046338:pharynx_unique
WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
WBPaper00047131:daf-2(e1370)_upregulated_N2-background
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00051305:vit-2(ac3)_upregulated
WBPaper00051558:aging_regulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin-Psora_downregulated
WBPaper00056139:soil-microbiota_upregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056446:hsb-1(cg116)_upregulated
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057041:unc-70(cas983)_downregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058691:cfp-1(tm6369)_downregulated
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00059224:tph-1(mg280)_upregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059763:neuron_expressed
WBPaper00060014:set-2(zr2012)_downregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061340:ADE
WBPaper00061340:ALN
WBPaper00061340:BWM_anterior
WBPaper00061340:DB
WBPaper00061340:DD
WBPaper00061340:IL1_parent
WBPaper00061340:Neuroblast_ADE_ADA
WBPaper00061340:Neuroblast_ALM_BDU
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061405:S.aureus_downregulated_starvation
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061508:P.mirabilis_12h_upregulated
WBPaper00061508:S.aureus_36h_upregulated
WBPaper00061527:sol-1-jnk-1_18695
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064871:hypoxia_downregulated_F1
WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
WBPaper00065258:anchor-cell_enriched
WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
WBPaper00065749:Heat-Shock_downregulated_N2
WBPaper00065835:Day5_vs_Day1_downregulated
WBPaper00065841:6_0
WBPaper00065841:10_0
WBPaper00065841:14_1
WBPaper00065841:107_0
WBPaper00066005:RAGA-1_degradation_somatic_upregulated
cgc4386_cluster_6_4
cgc4489_group_21
WBPaper00025032:cluster_5
WBPaper00025141:N2_Expressed_Genes
WBPaper00031003:0hr_muscle_enriched
WBPaper00031003:hlh_1_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00032165:differentially_expressed_with_age_medoid_1
WBPaper00034661:AgNPs_downregulated
WBPaper00036130:mir-243_up_regulated
WBPaper00036286:Pattern_D
WBPaper00037695:WC_5-day
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00042234:xpa-1_upregulated
WBPaper00055899:nitroguanidine_regulated
WBPaper00057098:SiO2-nanoparticles_upregulated
[cgc5767]:cluster_4
[cgc5767]:expression_class_E
[cgc5767]:expression_class_ET
[cgc5767]:expression_class_ET_max(83_min)
[cgc5767]:expression_class_E_pi(23_min)
[cgc5767]:expression_class_SE
[cgc5767]:expression_class_SET
[cgc5767]:expression_class_SE_pi(23_min)
Interaction (126)
WBProcessWBbiopr:00000025
Map_infoMapIIIPosition-0.669233Error0.000684
PositivePositive_cloneDS#CH134
R13A5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4202
Pseudo_map_position
Reference (109)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene