WormBase Tree Display for Gene: WBGene00001860

WBGene00001860 Evidence: Paper_evidence: WBPaper00005919
  SMap: S_parent: Sequence: F28B3
  Identity: Version: 1
    Name: CGC_name: him-1 Person_evidence: WBPerson261
      Sequence_name: F28B3.7
      Molecular_name: F28B3.7a
        F28B3.7a.1
        CE42002
        F28B3.7b
        CE39925
        F28B3.7b.1
      Other_name: smc-1 Person_evidence: WBPerson421
            WBPerson1819
        CELE_F28B3.7 Accession_evidence: NDB BX284601
      Public_name: him-1
    DB_info: Database: WormQTL gene WBGene00001860
        WormFlux gene WBGene00001860
        NDB locus_tag CELE_F28B3.7
        Panther gene CAEEL|WormBase=WBGene00001860|UniProtKB=O01789
          family PTHR18937
        NCBI gene 172116
        RefSeq protein NM_001047193.6
            NM_001047194.3
        SwissProt UniProtAcc O01789
        TREEFAM TREEFAM_ID TF101156
        UniProt_GCRP UniProtAcc O01789
        OMIM gene 300040
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info (13)
  Disease_info: Potential_model: DOID:6000 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11111)
      DOID:0070380 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11111)
      DOID:0080506 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11111)
  Molecular_info: Corresponding_CDS: F28B3.7a
      F28B3.7b
    Corresponding_CDS_history: F28B3.7:wp155
      F28B3.7a:wp186
    Corresponding_transcript: F28B3.7a.1
      F28B3.7b.1
    Other_sequence (66)
    Associated_feature: WBsf663794
      WBsf664180
      WBsf664181
      WBsf976678
      WBsf976679
      WBsf219342
  Experimental_info: RNAi_result (26)
    Expr_pattern: Expr2599
      Expr11146
      Expr12737
      Expr1011630
      Expr1031094
      Expr1149703
      Expr2012427
      Expr2030663
    Drives_construct: WBCnstr00036643
    Construct_product: WBCnstr00036643
    Antibody: WBAntibody00000634
    Microarray_results (24)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032031:DConiospora_upregulated_cDNA_24h
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_embryo_enriched
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00044760:germline_specific
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00048762:FOG-3_associated
      WBPaper00048988:neuron_expressed
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050743:elli-1(sam-3)_upregulated
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00054792:FOG-3_interacting
      WBPaper00054913:AKIR-1_interacting_protein
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056619:CEPsh_enriched
      WBPaper00058691:WDR-5.1_interacting_protein
      WBPaper00059328:mrps-5(RNAi)_upregulated_protein
      WBPaper00059605:MUT-16_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00059763:neuron_expressed
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061340:Neuroblast_ADF_AWB
      WBPaper00061340:Neuroblast_AWC_SAAVx
      WBPaper00061340:Neuroblast_IL1_IL2
      WBPaper00061340:Neuroblast_PVC_LUA
      WBPaper00061340:PLM_ALN_grandparent
      WBPaper00061340:PVQ_parent
      WBPaper00061340:RIC
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:cids-2_2203-attf-2_2451
      WBPaper00061527:kle-2_4298-vrk-1
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064201:SNA-3_interacting
      WBPaper00064315:mes-3(bn199)_downregulated_EGCs
      WBPaper00064315:mes-4(bn73)_downregulated_EGCs
      WBPaper00064716:paraquat_upregulated
      WBPaper00065149:lin-52(n771)_upregulated
      WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_downregulated
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_3d_0.2mM_Down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(23_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_F
      [cgc6390]:oogenesis-enriched
    Interaction (228)
    WBProcess: WBbiopr:00000099
  Map_info (4)
  Reference (51)
  Remark: let-526(h185) and let-127(h1880) are in the same strain (KR499) C01G8 rescues the early larval phenotype (let-526) unvailing the let-127's late larval phenotype.
  Method: Gene