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WormBase Tree Display for Gene: WBGene00009940

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Name Class

WBGene00009940SMapS_parentSequenceF52F12
IdentityVersion2
NameCGC_namestrl-1Person_evidenceWBPerson6837
Sequence_nameF52F12.7
Molecular_nameF52F12.7a
F52F12.7a.1
CE42711
F52F12.7b
CE10852
F52F12.7b.1
Other_nameCELE_F52F12.7Accession_evidenceNDBBX284601
Public_namestrl-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:50WBPerson1971EventImportedInitial conversion from CDS class of WS125
212 Apr 2012 16:34:57WBPerson2970Name_changeCGC_namestrl-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classstrl
Allele (24)
StrainWBStrain00037510
In_clusterconserved_miRNA_siRNA_cluster
RNASeq_FPKM (74)
GO_annotation00030887
00030888
00030889
00030890
00117496
Ortholog (44)
ParalogWBGene00012127Caenorhabditis elegansFrom_analysisTreeFam
WBGene00010505Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00017826Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionF52F12.7 is orthologous to the human gene STEROIDOGENIC ACUTE REGULATORY PROTEIN (STAR; OMIM:600617), which when mutated leads to disease.Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated06 Aug 2004 00:00:00
Automated_descriptionPredicted to enable lipid binding activity. Predicted to be involved in vesicle tethering to endoplasmic reticulum. Predicted to be located in endoplasmic reticulum membrane; endoplasmic reticulum-endosome membrane contact site; and late endosome membrane. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia. Is an ortholog of human STAR (steroidogenic acute regulatory protein).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050811Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11359)
Molecular_infoCorresponding_CDSF52F12.7a
F52F12.7b
Corresponding_CDS_historyF52F12.7:wp192
Corresponding_transcriptF52F12.7a.1
F52F12.7b.1
Other_sequence (17)
Associated_featureWBsf655797
WBsf656811
WBsf656812
WBsf218372
Experimental_infoRNAi_resultWBRNAi00048013Inferred_automaticallyRNAi_primary
WBRNAi00032633Inferred_automaticallyRNAi_primary
Expr_patternExpr1028193
Expr1034331
Expr1151828
Expr2017097
Expr2035233
Drives_constructWBCnstr00031799
Construct_productWBCnstr00031799
Microarray_results (22)
Expression_clusterWBPaper00032097:CGH-1-associated-mRNA
WBPaper00033065:isp-1-1(qm150)_upregulated
WBPaper00037946:EGL-5_interacting
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:bodywall-muscle_larva_enriched
WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
WBPaper00044128:daf-2(e1370)_downregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045417:128Q-huntingtin_upreglated
WBPaper00046691:P1_enriched
WBPaper00048988:neuron_expressed
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_embryo_SMARTseq
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053810:clk-1(qm30)_upregulated
WBPaper00053810:isp-1(qm150)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055648:germline_expressed
WBPaper00055827:pfd-6(gk493446)_upregulated
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056034:pals-25(jy9)_upregulated
WBPaper00056284:ints-6(t1903)_upregulated
WBPaper00056284:ints-11(RNAi)_upregulated
WBPaper00057288:Cold_downregulated_protein
WBPaper00057288:Cold_upregulated_transcript
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00059027:neuron-synapses_enriched
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
WBPaper00060278:atp-2(RNAi)_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061274:hypergravity_15xg_upregulated
WBPaper00061340:BWM_anterior
WBPaper00061340:DA
WBPaper00061340:DD
WBPaper00061340:mu_int_mu_anal
WBPaper00061340:Neuroblast_PVC_LUA
WBPaper00061340:Z1_Z4
WBPaper00061466:nath-10(icb99)_downregulated
WBPaper00061527:D1007.4-F33G12.2
WBPaper00061651:Distal_tip_cell_enriched
WBPaper00061651:hmc_enriched
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064130:Beta-Amyloid_upregulated_protein
WBPaper00064315:mes-4(bn73)_upregulated_EGCs
WBPaper00064494:postdauer_upregulated_AWA
WBPaper00064716:paraquat_upregulated
WBPaper00064789:Day9_vs_Day1_upregulated_neuron
WBPaper00064789:Day12_vs_Day1_upregulated_neuron
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065841:4_1
WBPaper00065841:4_2
WBPaper00065841:31_0
WBPaper00065841:110_1
WBPaper00065975:P-body_vs_oocyte_enriched
WBPaper00065975:P-body_vs_WholeAnimal_enriched
WBPaper00066062:xrep-4(lax137)_upregulated
cgc4386_cluster_3_3
cgc4489_group_25
WBPaper00006465:II_ethanol_late_induction
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00030985:Photorhabdus_luminescens_upregulated
WBPaper00031003:0hr_muscle_enriched
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:hlh_1_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00032165:A_to_C_transit_decreased
WBPaper00035588:alg-1(-)_upregulated
WBPaper00035905:FBF-1_Associated
WBPaper00036123:Atrazine_regulated
WBPaper00036286:Pattern_D
WBPaper00037611:RNP-8-associated
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00041370:spg-7(RNAi)_upregulated
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_51h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045263:isp-1(qm150)_upregulated
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00045263:ProLongevity-mtROS_upregulated
WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
WBPaper00048989:N2_allantoin_upregulated
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00053236:Starvation_regulated_GR1307
[cgc5767]:cluster_2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(83_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
InteractionWBInteraction000264141
WBInteraction000354274
WBInteraction000373343
WBInteraction000420659
WBInteraction000459459
WBInteraction000461309
Map_infoMapIPosition4.06833
PositivePositive_cloneF52F12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00048210
WBPaper00055090
WBPaper00057279
WBPaper00064789
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene