WormBase Tree Display for Gene: WBGene00010456

WBGene00010456 SMap: S_parent: Sequence: K01C8
  Identity: Version: 2
    Name: CGC_name: srdh-1 Person_evidence: WBPerson9055
            WBPerson55847
      Sequence_name: K01C8.1
      Molecular_name: K01C8.1
        K01C8.1.1
        CE36943
        K01C8.1.2
      Other_name: CELE_K01C8.1 Accession_evidence: NDB BX284602
      Public_name: srdh-1
    DB_info: Database: AceView gene 2I557
        WormQTL gene WBGene00010456
        WormFlux gene WBGene00010456
        NDB locus_tag CELE_K01C8.1
        Panther gene CAEEL|WormBase=WBGene00010456|UniProtKB=Q21080
          family PTHR48078
        NCBI gene 174326
        RefSeq protein NM_063340.5
        TREEFAM TREEFAM_ID TF314863
        TrEMBL UniProtAcc Q21080
        UniProt_GCRP UniProtAcc Q21080
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 27 Oct 2021 12:29:35 WBPerson1983 Name_change: CGC_name: srdh-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: srdh
    Allele (34)
    RNASeq_FPKM (74)
    GO_annotation: 00070245
      00070246
      00070247
      00070248
      00070249
      00070250
      00117863
      00117864
    Ortholog (32)
    Paralog (12)
    Structured_description: Automated_description: Predicted to enable L-serine ammonia-lyase activity and L-threonine ammonia-lyase activity. Predicted to be involved in L-serine catabolic process; isoleucine biosynthetic process; and threonine catabolic process. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: K01C8.1
    Corresponding_CDS_history: K01C8.1:wp127
    Corresponding_transcript: K01C8.1.1
      K01C8.1.2
    Other_sequence (81)
    Associated_feature: WBsf657954
      WBsf657955
      WBsf988687
      WBsf1012663
      WBsf221724
      WBsf221725
  Experimental_info: RNAi_result: WBRNAi00033544 Inferred_automatically: RNAi_primary
      WBRNAi00075854 Inferred_automatically: RNAi_primary
      WBRNAi00016385 Inferred_automatically: RNAi_primary
      WBRNAi00049602 Inferred_automatically: RNAi_primary
      WBRNAi00033812 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1028087
      Expr1034561
      Expr1153333
      Expr2004642
      Expr2022870
    Drives_construct: WBCnstr00031406
    Construct_product: WBCnstr00031406
    Microarray_results (20)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044656:tatn-1(qd182)_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045257:bar-1(ga80)_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00049954:BPA_downregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_25C
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:hypodermis_enriched
      WBPaper00050990:hypodermis_expressed
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00051305:vit-2(ac3)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00053140:DecreasingResponse_20nmAgCit
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055137:S.maltophilia_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056139:gut-microbiota_downregulated
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056284:ints-1(RNAi)_upregulated
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057254:MWCNT_downregulated_mRNA
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058948:PA14_upregulated
      WBPaper00059027:neuron-synapses_enriched
      WBPaper00059254:CSR-1_interacting
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059373:stt-3(RNAi)_downregulated
      WBPaper00059537:ngn-1(ok2200)_upregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00059816:crh-1(n3315)_downrgulated
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060871:M.humicola-infection_48h_regulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061045:Y56A3A.22(cck200)_upregulated
      WBPaper00061081:E.faecalis_downregulated_N2
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:microgravity_downregulated
      WBPaper00061405:S.aureus_downregulated_starvation
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:F35C8.5-T10B5.7
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_downregulated
      WBPaper00061651:RIC_enriched
      WBPaper00061692:acivicin_upregulated
      WBPaper00061818:ELKS-1_interacting
      WBPaper00061823:mex-3(spr9)_downregulated
      WBPaper00061995:mter-4(syb3662syb3403)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062184:PA14_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062354:H.zoospora_12h_regulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064122:vulva_transcriptome
      WBPaper00064130:Beta-Amyloid_upregulated_protein
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064602:egl-9(sa307)_downregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065272:dhgd-1(tm6671)_downregulated
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065746:eat-2(ad1113)_upregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:2_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4489_group_10
      WBPaper00025099:MA_specific
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00027342:alpha-Synuclein(WT)_upregulated
      WBPaper00030985:Enterococcus_faecalis_downregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00032165:differentially_expressed_with_age_medoid_6
      WBPaper00032948:FedUp
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035227:heat_shock_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-7_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00036286:Pattern_I
      WBPaper00036383:ash-2_Day8_regulated
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00040184:hcf-1down_sir-2.1down_daf-2down
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040963:Q50_down
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00055435:MUA-AuNP-3_downregulated
    Interaction (119)
  Map_info: Map: II Position: 0.755243
    Positive: Positive_clone: K01C8 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene