WormBase Tree Display for Gene: WBGene00012316

WBGene00012316 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 2
    Name: CGC_name: ctps-1 Person_evidence: WBPerson261
      Sequence_name: W06H3.3
      Molecular_name: W06H3.3a
        W06H3.3a.1
        CE29830
        W06H3.3b
        CE54462
        W06H3.3b.1
      Other_name: CELE_W06H3.3 Accession_evidence: NDB BX284605
      Public_name: ctps-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 27 Apr 2012 17:06:28 WBPerson2970 Name_change: CGC_name: ctps-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ctps
    Allele (174)
    Strain: WBStrain00002678
    RNASeq_FPKM (74)
    GO_annotation (20)
    Contained_in_operon: CEOP5456
    Ortholog (46)
    Structured_description: Automated_description: Predicted to enable CTP synthase activity and identical protein binding activity. Predicted to be involved in CTP biosynthetic process and pyrimidine nucleobase biosynthetic process. Predicted to be located in cytoophidium and cytoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in biliary tract benign neoplasm; colorectal cancer; and immunodeficiency 24. Is an ortholog of human CTPS1 (CTP synthase 1) and CTPS2 (CTP synthase 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9256 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2520)
      DOID:0111938 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2519)
      DOID:0050625 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2519)
  Molecular_info: Corresponding_CDS: W06H3.3a
      W06H3.3b
    Corresponding_CDS_history: W06H3.3:wp68
    Corresponding_transcript: W06H3.3a.1
      W06H3.3b.1
    Other_sequence (67)
    Associated_feature: WBsf662165
      WBsf662166
      WBsf662167
      WBsf1002532
  Experimental_info: RNAi_result (16)
    Expr_pattern: Chronogram297
      Expr6844
      Expr14957
      Expr1012763
      Expr1035449
      Expr1158458
      Expr2010579
      Expr2028819
    Drives_construct: WBCnstr00003220
    Microarray_results (18)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00044030:nhr-8(hd117)_downregulated
      WBPaper00044037:eat-2_downregulated
      WBPaper00044128:daf-2(e1370)_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049954:BPS_downregulated
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051461:pig-1(gm344)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_downregulated_L1_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056034:pals-25(jy9)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058948:PA14_upregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061340:g1A_parent
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:tub-2_4713-daf-2_5288
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_upregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065315:mating_upregulated_Day2-7
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      WBPaper00036123:Atrazine_regulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00048989:N2_rapamycin_downregulated
      [cgc6390]:oogenesis-enriched
    Interaction (160)
  Map_info: Map: V Position: 11.1834
    Positive: Positive_clone: W06H3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00059294
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene