WormBase Tree Display for Gene: WBGene00012933

WBGene00012933 SMap: S_parent: Sequence: Y47D3A
  Identity: Version: 2
    Name: CGC_name: mib-1 Paper_evidence: WBPaper00040136
      Sequence_name: Y47D3A.22
      Molecular_name: Y47D3A.22
        Y47D3A.22.1
        CE32261
      Other_name: CELE_Y47D3A.22 Accession_evidence: NDB BX284603
      Public_name: mib-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 02 Sep 2011 14:03:09 WBPerson2970 Name_change: CGC_name: mib-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mib
    Allele (94)
    Strain: WBStrain00051247
    RNASeq_FPKM (74)
    GO_annotation: 00099092
      00099093
    Contained_in_operon: CEOP3843
    Ortholog (40)
    Structured_description: Automated_description: Predicted to enable ubiquitin protein ligase activity. Expressed in vulva. Human ortholog(s) of this gene implicated in left ventricular noncompaction. Is an ortholog of human MIB1 (MIB E3 ubiquitin protein ligase 1) and MIB2 (MIB E3 ubiquitin protein ligase 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0060480 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:21086)
  Molecular_info: Corresponding_CDS: Y47D3A.22
    Corresponding_CDS_history: Y47D3A.22:wp52
    Corresponding_transcript: Y47D3A.22.1
    Other_sequence: CRC02014_1
    Associated_feature: WBsf994328
      WBsf994329
      WBsf227564
  Experimental_info: RNAi_result: WBRNAi00089665 Inferred_automatically: RNAi_primary
      WBRNAi00056746 Inferred_automatically: RNAi_primary
      WBRNAi00089664 Inferred_automatically: RNAi_primary
      WBRNAi00056745 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr14447
      Expr14448
      Expr1023212
      Expr1035730
      Expr1160207
      Expr2013553
      Expr2031786
    Drives_construct: WBCnstr00040880
    Microarray_results (17)
    Expression_cluster: WBPaper00033070:Rhine_downregulated
      WBPaper00037946:LIN-39_interacting
      WBPaper00040560:hpl-2_L3_upregulated
      WBPaper00044736:rising_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00048923:Aging_regulated
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00048988:neuron_expressed
      WBPaper00049217:TCER-1_downregulated
      WBPaper00050015:ifg-1(RNAi)_upregulated
      WBPaper00050193:lsm-1(tm3585)_upregulated_L3
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053289:DREAM-target
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00054571:BPA_F3_germline_downregulated
      WBPaper00055648:sperm_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057140:pptr-1(tm3103)_downregulated
      WBPaper00057161:meg-3(tm4259)_meg-4(ax2026)_downregulated_endo-siRNA_targets
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060886:met-2(n4256)_upregulated
      WBPaper00060886:spr-5(by101);met-2(n4256)_upregulated
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061340:AIN_parent
      WBPaper00061340:Neuroblast_AIZ_FLP
      WBPaper00061340:Neuroblast_ASJ_AUA
      WBPaper00061340:Parent_of_AMsh_URB
      WBPaper00061340:Parent_of_MI_pm1DR
      WBPaper00061340:URA_parent
      WBPaper00061527:sfxn-1.4-K11H3.2
      WBPaper00062056:dpl-1(n2994)_downregulated
      WBPaper00062056:lin-35(n745)_downregulated
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062056:met-2(n4256)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064716:paraquat_downregulated
      WBPaper00065158:AFD_enriched
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065995:M.humicola-extract_downregulated_N2
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      cgc4489_group_20
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026980:intestine_enriched
      WBPaper00034739:N2lessDR1350
      WBPaper00035227:heat_shock_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_E
      WBPaper00037147:heatshock_upregulated
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045263:ProLongevity-mtROS_downregulated
      [cgc6390]:Cluster_D
      [cgc6390]:spermatogenesis-enriched
    Interaction: WBInteraction000033058
      WBInteraction000033059
      WBInteraction000033060
      WBInteraction000034030
      WBInteraction000518780
      WBInteraction000575609
  Map_info: Map: III Position: 8.32037 Error: 0.023566
    Positive: Positive_clone: Y47D3A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027315
    WBPaper00038491
    WBPaper00040136
    WBPaper00048252
    WBPaper00053831
    WBPaper00054557
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene