Y66A7A.2 encodes an ortholog of Pop5, a protein subunit shared by theendoribonucleases RNase MRP and RNAse P; RNAse MRP cleavesmitochondrial RNA in mitochondrial DNA synthesis, nucleolar pre-rRNA inribosome synthesis, and at least one mRNA (CLB2) involved in cell-cycleregulation; RNAse P cleaves tRNA precursors to produce their mature 5'end; Y66A7A.2 is evolutionarily ubiquitous among eukaryotes.
Predicted to enable ribonuclease P RNA binding activity and ribonuclease P activity. Predicted to be involved in rRNA processing and tRNA processing. Predicted to be located in nucleolus. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Is an ortholog of human POP5 (POP5 homolog, ribonuclease P/MRP subunit).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.