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WormBase Tree Display for Gene: WBGene00013980

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Name Class

WBGene00013980SMapS_parentSequenceZK507
IdentityVersion2
NameCGC_namedos-1Person_evidenceWBPerson242
Sequence_nameZK507.4
Molecular_nameZK507.4
ZK507.4.1
CE38765
Other_nameCELE_ZK507.4Accession_evidenceNDBBX284603
Public_namedos-1
DB_infoDatabaseAceViewgene3K191
WormQTLgeneWBGene00013980
WormFluxgeneWBGene00013980
NDBlocus_tagCELE_ZK507.4
PanthergeneCAEEL|WormBase=WBGene00013980|UniProtKB=P34636
familyPTHR35015
NCBIgene191338
RefSeqproteinNM_066616.6
SwissProtUniProtAccP34636
TREEFAMTREEFAM_IDTF315672
UniProt_GCRPUniProtAccP34636
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:55WBPerson1971EventImportedInitial conversion from CDS class of WS125
224 Jan 2008 10:42:49WBPerson2970Name_changeCGC_namedos-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdos
Allele (42)
StrainWBStrain00032542
RNASeq_FPKM (74)
GO_annotation00043626
00043627
00043628
Ortholog (22)
ParalogWBGene00003887Caenorhabditis elegansFrom_analysisPanther
WBGene00003891Caenorhabditis elegansFrom_analysisTreeFam
Panther
WBGene00019331Caenorhabditis elegansFrom_analysisTreeFam
Panther
WBGene00019640Caenorhabditis elegansFrom_analysisTreeFam
Structured_descriptionConcise_descriptiondos-1 encodes an unfamilar protein with no clear orthologs outside of nematodes; DOS-1 is paralogous to OSM-7, K02F3.7, and ZK507.4, has a predicted signal sequence with 12 conserved cysteine residues, and may be secreted; DOS-1 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00028499
Curator_confirmedWBPerson567
Date_last_updated29 Mar 2008 00:00:00
Automated_descriptionPredicted to enable Notch binding activity. Predicted to be involved in positive regulation of Notch signaling pathway. Predicted to be located in extracellular space.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK507.4
Corresponding_CDS_historyZK507.4:wp144
Corresponding_transcriptZK507.4.1
Other_sequenceCJC05627_1
Associated_featureWBsf645462
WBsf659386
WBsf993572
WBsf225519
WBsf225520
Experimental_infoRNAi_resultWBRNAi00059466Inferred_automaticallyRNAi_primary
WBRNAi00006362Inferred_automaticallyRNAi_primary
WBRNAi00022036Inferred_automaticallyRNAi_primary
WBRNAi00088838Inferred_automaticallyRNAi_primary
Expr_patternExpr1020576
Expr1162889
Expr2011032
Expr2029269
Drives_constructWBCnstr00029398
Construct_productWBCnstr00029398
Microarray_results (18)
Expression_clusterWBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:hypodermis_larva_enriched
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
WBPaper00042561:smg-2(RNAi)_downregulated
WBPaper00042561:smgl-2(RNAi)_upregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00045017:blmp-1(tm548)_upregulated
WBPaper00045521:Gender_Neutral
WBPaper00045774:clk-1_upregulated
WBPaper00045861:set-2(ok952)_upregulated
WBPaper00045861:wdr-5(ok1417)_upregulated
WBPaper00048611:MnCl2_downregulated
WBPaper00048952:glucose_induced
WBPaper00048988:neuron_expressed
WBPaper00049018:ham-3(RNAi)_downregulated
WBPaper00049134:hpk-1(pk1393)_upregulated
WBPaper00049732:blmp-1(tm548)_vs_N2_upregulated
WBPaper00049736:daf-2(e1370)_downregulated_15deg-then-25deg(12hr)
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050990:hypodermis_enriched
WBPaper00050990:hypodermis_expressed
WBPaper00051257:Levamisole_upregulated
WBPaper00051404:alg-2(ok304)_upregulated
WBPaper00053092:procyanidins_downregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(icb38)_downregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster1
WBPaper00053810:isp-1(qm150)_downregulated
WBPaper00053810:nuo-6(qm200)_downregulated
WBPaper00053814:15C_downregulated_PY79
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Psora_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00055941:nuo-6(qm200)_downregulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00057068:Cadmium_upregulated
WBPaper00057154:HeatShock_downregulated_mRNA
WBPaper00057154:HeatShock_upregulated_miRNA-target
WBPaper00057265:metaformin_upregulated_OP50
WBPaper00057265:metaformin_upregulated_OP50-MR
WBPaper00058711:wdr-5(ok1417)_upregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058725:sftb-1(cer39)_downregulated
WBPaper00058948:npr-8(ok1439)_downregulated_OP50
WBPaper00058969:RIS_depleted
WBPaper00059027:neuron-synapses_enriched
WBPaper00059117:B.subtilis_upregulated
WBPaper00059253:sucrose_stearic-acid_upregulated
WBPaper00059253:sucrose_upregulated
WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
WBPaper00059598:HeatShock_downregulated
WBPaper00059735:glucose_upregulated_lpin-1(RNAi)
WBPaper00059735:glucose_upregulated_N2
WBPaper00059816:crh-1(n3315)_downrgulated
WBPaper00059895:wounding_upregulated
WBPaper00060273:isp-1(qm150)_upregulated
WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
WBPaper00060661:hypoxia_upregulated
WBPaper00060661:sensory-neuron_depleted
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060764:swsn-9(ok1354)_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060871:M.humicola-infection_48h_regulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061340:ALM_BDU
WBPaper00061340:ALN
WBPaper00061340:AVH
WBPaper00061340:I5
WBPaper00061340:PLM
WBPaper00061340:RIH
WBPaper00061341:28C_24h_upregulated
WBPaper00061527:K07E1.1-Y71F9B.13_934
WBPaper00061530:nhr-49(e2144)_upregulated
WBPaper00061651:HSN_enriched
WBPaper00061653:alh-4(hj221)_upregulated
WBPaper00061699:daf-18(ok480)_upregulated
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00061952:daf-18(nr2037)_upregulated
WBPaper00062156:jmjd-5(zr1234)_upregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062184:PA14_downregulated
WBPaper00062193:daf-16(RNAi)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062347:blmp-1(tm548)_upregulated
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
WBPaper00062715:blmp-1(s71)_upregulated
WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064473:ets-4(rrr16)_downregulated
WBPaper00064494:postdauer_downregulated_WholeAnimal
WBPaper00064769:him-17(me24)_downregulated
WBPaper00064871:hypoxia_downregulated_F1
WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065581:hpk-1(pk1393)_upregulated
WBPaper00065749:Heat-Shock_downregulated_N2
WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
WBPaper00065841:17_0
WBPaper00065841:33_0
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00066062:xrep-4(lax137)_upregulated
cgc4489_group_5
WBPaper00026980:intestine_enriched
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00036464:S.aureus-RN6390_regulated
WBPaper00040963:TA100_up
WBPaper00040963:TA300_up
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00045263:isp-1(qm150)_downregulated
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
WBPaper00053236:daf-16(mgDF50)_regulated_Starved
WBPaper00053236:Starvation_regulated_N2
InteractionWBInteraction000235998
WBInteraction000334941
Map_infoMapIIIPosition0.16456Error0.000331
PositivePositive_cloneZK507Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00032102
WBPaper00038400
WBPaper00040714
WBPaper00065331
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene