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WormBase Tree Display for Gene: WBGene00015326

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Name Class

WBGene00015326SMapS_parentSequenceC02B10
IdentityVersion2
NameCGC_nameivd-1
Sequence_nameC02B10.1
Molecular_nameC02B10.1
C02B10.1.1
CE16798
Other_nameCELE_C02B10.1Accession_evidenceNDBBX284604
Public_nameivd-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:55WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
226 Feb 2007 14:38:18WBPerson2970Name_changeCGC_nameivd-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classivd
Allele (29)
StrainWBStrain00001621
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (39)
Paralog (22)
Structured_descriptionConcise_descriptionivd-1 encodes an isovaleryl-CoA dehydrogenase; this function has been verified by both sequence homology and direct biochemical assay.Paper_evidenceWBPaper00004637
WBPaper00004732
Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated11 Nov 2008 00:00:00
Automated_descriptionPredicted to enable isovaleryl-CoA dehydrogenase activity. Involved in regulation of response to oxidative stress. Predicted to be located in mitochondrion. Expressed in head. Human ortholog(s) of this gene implicated in isovaleric acidemia. Is an ortholog of human IVD (isovaleryl-CoA dehydrogenase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:14753Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6186)
DOID:9252Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6186)
Molecular_infoCorresponding_CDSC02B10.1
Corresponding_transcriptC02B10.1.1
Other_sequence (77)
Associated_featureWBsf667925
WBsf996432
WBsf1017332
WBsf230050
WBsf230051
WBsf230052
WBsf230053
Experimental_infoRNAi_resultWBRNAi00039385Inferred_automaticallyRNAi_primary
WBRNAi00108514Inferred_automaticallyRNAi_primary
WBRNAi00009964Inferred_automaticallyRNAi_primary
WBRNAi00102599Inferred_automaticallyRNAi_primary
Expr_patternChronogram1081
Expr5102
Expr1015733
Expr1036563
Expr1143502
Expr2012878
Expr2031112
Drives_constructWBCnstr00002460
WBCnstr00028933
Construct_productWBCnstr00028933
Microarray_results (22)
Expression_clusterWBPaper00028451:Low_abundance_spermatogenesis_enriched
WBPaper00031040:TGF-beta_adult_downregulated
WBPaper00032425:down_in_lin-35
WBPaper00032425:down_in_zfp-1
WBPaper00032528:L3_enriched
WBPaper00037047:insoluble_protein
WBPaper00037950:coelomocytes_embryo_enriched
WBPaper00037950:coelomocytes_embryo_SelectivelyEnriched
WBPaper00038118:aak-2(gt33)_upregulated
WBPaper00038289:oocyte_protein
WBPaper00040446:insoluble_protein
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:flat_dev_expression
WBPaper00044746:aging_downregulated_HeatShock
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Gender_Neutral
WBPaper00045774:clk-1_downregulated
WBPaper00045774:clk-1_downregulated_CoQ10_independent
WBPaper00046509:htz-1(ok3099)_downregulated
WBPaper00046509:lin-35(n745)_downregulated
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050698:DEP-1_interacting
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:seam_expressed
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
WBPaper00051311:VGLN-1-interacting
WBPaper00051558:aging_regulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00053814:15C_downregulated_PY79
WBPaper00055049:S.gordonii_downregulated
WBPaper00055354:eat-2(ad1116)_upregulated
WBPaper00055354:Metformin_downregulated
WBPaper00055354:Rapamycin-Allantoin_upregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055827:pfd-6(gk493446)_downregulated
WBPaper00055971:nhl-2(ok818)_20C_downregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056275:P.aeruginosa_downregulated
WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
WBPaper00056275:P.aeruginosa_upregulated
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00056826:hmc_biased
WBPaper00057041:spc-1(cas971)_upregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00058691:cfp-1(tm6369)_upregulated
WBPaper00058691:CFP-1_interacting_protein
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058801:ceh-60(lst466)_downregulated_protein
WBPaper00058948:PA14_upregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_protein
WBPaper00059605:MUT-16_interacting
WBPaper00059895:wounding_downregulated
WBPaper00060661:sensory-neuron_depleted
WBPaper00060683:hlh-11(overexpression)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061340:AVD
WBPaper00061340:AVG
WBPaper00061341:28C_24h_downregulated
WBPaper00061341:28C_48h_downregulated
WBPaper00061377:MYRF-1_interacting
WBPaper00061527:F43G9.13-F33D11.12
WBPaper00061527:tars-1-AFFX-r2-3026-5_at
WBPaper00061651:Spermatheca_enriched
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062446:nhr-8(hd117)_downregulated
WBPaper00062498:PPM-1.D_interacting
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064315:mes-4(bn73)_downregulated_EGCs
WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
WBPaper00064494:postdauer_downregulated_AWA
WBPaper00065086:JU1400_N.ausubeli_regulated
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065086:JU1400_N.ironsii_regulated
WBPaper00065086:N2_N.ausubeli_regulated
WBPaper00065158:AFD_depleted
WBPaper00065373:sek-1(km4)_upregulated_Ref
WBPaper00065841:49_0
cgc4386_cluster_1_2
cgc4489_group_2
WBPaper00025032:cluster_1
WBPaper00025032:cluster_6
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Enriched_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:Resveratrol_regulated_N2
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00027342:alpha-Synuclein(WT)_upregulated
WBPaper00027722:Microbacterium_nematophilum_downregulated
WBPaper00030839:Embryo_A_Class
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030985:Enterococcus_faecalis_downregulated
WBPaper00031532:Larva_Pan_Neuronal_Depleted
WBPaper00032948:FedUp
WBPaper00036286:Pattern_G
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00040876:mir-35_upregulated
WBPaper00040985:AIN-2_asynchronous_intestine
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_EtBr-exposed_51h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_24h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00045263:0.1mM-paraquat_downregulated
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00048989:N2_allantoin_downregulated
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:cluster_1
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MD_pd(41_min)
[cgc5767]:expression_class_MD_pd(53_min)
[cgc5767]:expression_class_SM
[cgc5767]:expression_class_SMD
Interaction (23)
Map_infoMapIVPosition1.43936Error0.002365
PositivePositive_cloneC02B10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00043054
WBPaper00045076
WBPaper00055090
WBPaper00060459
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene