WormBase Tree Display for Gene: WBGene00018696

WBGene00018696 SMap: S_parent: Sequence: F52E1
  Identity: Version: 2
    Name: CGC_name: pho-6 Person_evidence: WBPerson411
            WBPerson261
      Sequence_name: F52E1.8
      Molecular_name: F52E1.8
        F52E1.8.1
        CE47366
      Other_name: CELE_F52E1.8 Accession_evidence: NDB BX284605
      Public_name: pho-6
    DB_info: Database: AceView gene 5I870
        WormQTL gene WBGene00018696
        WormFlux gene WBGene00018696
        NDB locus_tag CELE_F52E1.8
        Panther gene CAEEL|WormBase=WBGene00018696|UniProtKB=Q20662
          family PTHR11567
        NCBI gene 186114
        RefSeq protein NM_072766.4
        TrEMBL UniProtAcc Q20662
        UniProt_GCRP UniProtAcc Q20662
        OMIM gene 606362
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 04 Nov 2008 10:21:23 WBPerson2970 Name_change: CGC_name: pho-6
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pho
    Allele (24)
    RNASeq_FPKM (74)
    GO_annotation: 00068726
      00068727
    Ortholog (38)
    Paralog (23)
    Structured_description: Automated_description: Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J and prostate cancer. Is an ortholog of human ACP2 (acid phosphatase 2, lysosomal); ACP3 (acid phosphatase 3); and ACP4 (acid phosphatase 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080953 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14376)
      DOID:10283 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:125)
  Molecular_info: Corresponding_CDS: F52E1.8
    Corresponding_CDS_history: F52E1.8:wp230
    Corresponding_transcript: F52E1.8.1
    Other_sequence: CRC12498_1
      BUC00248_1
      CBC08769_1
      CR07929
    Associated_feature: WBsf234079
      WBsf234080
  Experimental_info: RNAi_result: WBRNAi00047989 Inferred_automatically: RNAi_primary
      WBRNAi00032619 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1020738
      Expr1151804
      Expr2014909
      Expr2033145
    Microarray_results (18)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:excretory-cell_larva_enriched
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00044316:HgCl2_20uM_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(gk119)_upregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046496:Rifampicin_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00048611:MnCl2_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049489:AMsh-glia_enriched
      WBPaper00049498:npr-1(ur89)_regulated_1
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049635:dop-1(vs100)_upregulated
      WBPaper00050193:cec-4(ok3124)_upregulated_L1
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050561:indole_10-fold_upregulated
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00051021:4-bromodiphenyl-ether_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00052856:Cadmium_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053140:IncreasingResponse_20nmAgCit
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053318:mir-71(n4115)_upregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055103:thoc-5(wy822)_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055648:male-seminal-vesicle_expressed
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056284:ints-11(RNAi)_upregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00057041:spc-1(cas971)_downregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00058598:mex-1(or286)_downregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059231:alh-6(lax105)_L4_upregulated
      WBPaper00059253:stearic-acid_upregulated
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060871:M.humicola-infection_24h_regulated
      WBPaper00060909:atfs-1(et18)_downregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061274:microgravity_downregulated
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061357:mett-10(ok2204)_upregulated_OP50
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061527:T16H12.9-kin-9_20752
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00062103:neuron_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062197:mec-8_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062354:H.zoospora_12h_regulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062672:dcp-66(RNAi)_upregulated
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00062715:blmp-1(s71)_upregulated
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064532:pals-22(jy3)_upregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064532:pals-25(jy111)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064871:hypoxia_downregulated_F3
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065749:Heat-Shock_downregulated_N2
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_downregulated_Day11
      WBPaper00065841:45_0
      WBPaper00065841:65_0
      WBPaper00065841:84_0
      WBPaper00065841:141_0
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065995:M.humicola-extract_downregulated_N2
      WBPaper00066004:ceh-14(ch3)_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      cgc4489_group_17
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_N2
      WBPaper00029437:dcr-1_upregulated
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00032948:FedUp
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_F
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00044535:male_upregulated
      WBPaper00045015:nhr-25(RNAi)_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048637:lin-35(n745)_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_upregulated_L1
      WBPaper00053827:pyoverdine_upregulated
    Interaction: WBInteraction000199411
      WBInteraction000233497
      WBInteraction000309662
      WBInteraction000329328
  Map_info: Map: V Position: 1.38427 Error: 0.004218
    Positive: Positive_clone: F52E1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00065080
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene