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WormBase Tree Display for Gene: WBGene00019481

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Name Class

WBGene00019481SMapS_parentSequenceK07C11
IdentityVersion2
NameCGC_namecogc-6Paper_evidenceWBPaper00026979
Person_evidenceWBPerson449
Sequence_nameK07C11.9
Molecular_nameK07C11.9
K07C11.9.1
CE07351
Other_nameCELE_K07C11.9Accession_evidenceNDBBX284605
Public_namecogc-6
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:01WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
216 Jan 2006 17:10:26WBPerson2970Name_changeCGC_namecogc-6
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcogc
Allele (33)
In_clusterconserved_miRNA_siRNA_cluster
RNASeq_FPKM (74)
GO_annotation00071029
00071030
00071031
00071032
00071033
00071034
00071035
00071036
00124323
00124324
Ortholog (39)
Structured_descriptionConcise_descriptioncogc-6 encodes an ortholog of mammalian COG-6, a subunit of lobe B ofthe conserved oligomeric Golgi complex (COGC); COGC-6 is weakly requiredfor normal gonadal distal tip cell migration, a process that alsorequires seven other orthologs of COGC subunits; like other lobe Bsubunits in both C. elegans and S. cerevisiae, COGC-6 is only partiallyrequired for normal function, while lobe A subunits are stronglyrequired in either worms or yeast.Paper_evidenceWBPaper00026979
WBPaper00028363
WBPaper00028599
WBPaper00028603
Curator_confirmedWBPerson567
Date_last_updated25 Oct 2006 00:00:00
Automated_descriptionInvolved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIl. Is an ortholog of human COG6 (component of oligomeric golgi complex 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070264Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18621)
Molecular_infoCorresponding_CDSK07C11.9
Corresponding_transcriptK07C11.9.1
Other_sequenceCR01125
CBC01817_1
CR09438
CRC04217_1
CBC00410_1
FD515230.1
CSC01446_1
Associated_featureWBsf652832
WBsf668666
WBsf669150
WBsf1000599
WBsf1019992
WBsf234047
WBsf234048
WBsf234049
Experimental_infoRNAi_resultWBRNAi00016704Inferred_automaticallyRNAi_primary
WBRNAi00064304Inferred_automaticallyRNAi_primary
WBRNAi00076551Inferred_automaticallyRNAi_primary
WBRNAi00095102Inferred_automaticallyRNAi_primary
WBRNAi00099108Inferred_automaticallyRNAi_primary
WBRNAi00095103Inferred_automaticallyRNAi_primary
WBRNAi00050127Inferred_automaticallyRNAi_primary
WBRNAi00034056Inferred_automaticallyRNAi_primary
WBRNAi00002384Inferred_automaticallyRNAi_primary
Expr_patternExpr1027185
Expr1038417
Expr1153828
Expr2010295
Expr2028537
Drives_constructWBCnstr00025808
Construct_productWBCnstr00025808
Microarray_results (21)
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:intestine_embryo_enriched
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00044426:rotenone_24h_downregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045521:Gender_Neutral
WBPaper00048988:neuron_expressed
WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
WBPaper00050370:dpy-21(e428)_L3_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053289:DREAM-target
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00053810:nuo-6(qm200)_downregulated
WBPaper00055334:DLC-1_interacting
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056826:hmc_biased
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061340:g1A_g1P
WBPaper00061340:hmc_and_homolog
WBPaper00061340:mc3
WBPaper00061340:Pharyngeal_marginal_cell
WBPaper00061340:T
WBPaper00061527:F43G9.13-F33D11.12
WBPaper00061527:pbs-3_18439-rpn-5
WBPaper00061651:Coelomocyte_enriched
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00062193:hsf-1(RNAi)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00064716:paraquat_upregulated
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065373:sek-1(km4)_downregulated_Ref
WBPaper00065975:P-body_vs_oocyte_enriched
WBPaper00065975:P-body_vs_WholeAnimal_enriched
WBPaper00066062:xrep-4(lax137)_upregulated
cgc4386_cluster_5_6
cgc4489_group_8
cgc4489_group_25
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00032948:FedUp
WBPaper00035588:alg-1(-)_upregulated
WBPaper00035905:FBF-1_Associated
WBPaper00036286:Pattern_H
WBPaper00040210:Chlorpyrifos_24C_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
WBPaper00045960:L4-lethargus_downregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
WBPaper00057098:SiO2-nanoparticles_upregulated
[cgc5767]:cluster_68
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MD_pd(PC32)
[cgc5767]:expression_class_SM
[cgc5767]:expression_class_SMD
[cgc6390]:Cluster_E
[cgc6390]:herm_sex-enriched
[cgc6390]:intrinsic
Interaction (37)
Map_infoMapVPosition1.22329Error0.010338
PositivePositive_cloneK07C11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5659
4928
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00041771
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene