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WormBase Tree Display for Gene: WBGene00023452

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Name Class

WBGene00023452SMapS_parentSequenceD1007
IdentityVersion2
NameCGC_namemir-353Person_evidenceWBPerson18
Sequence_nameD1007.17
Molecular_nameD1007.17
D1007.17a
Other_namecel-mir-353RemarkmiRBase V21 import
CELE_D1007.17Accession_evidenceNDBBX284601
Public_namemir-353
DB_infoDatabasemiRBaseaccMI0000752
NDBlocus_tagCELE_D1007.17
NCBIgene3565490
RefSeqproteinNR_002333.2
RNAcentralURSidURS000022AB06
URS00004A5363
SpeciesCaenorhabditis elegans
HistoryVersion_change122 Jul 2004 12:37:16WBPerson1849EventCreated
226 Jul 2004 10:44:31WBPerson1971Name_changeCGC_namemir-353
StatusLive
Gene_infoBiotypeSO:0001265
Gene_classmir
AlleleWBVar01499919
WBVar01499786
WBVar01499985
WBVar00323167
WBVar01498959
RNASeq_FPKM (74)
Structured_descriptionConcise_descriptionmir-353 encodes a microRNA, a small non-protein coding RNA and seems to have a potential ortholog in C. briggsae; many of the known microRNAs are involved in post-transcriptional regulation of genes; the precise function of miR-353 is unknown.Paper_evidenceWBPaper00024441
Curator_confirmedWBPerson324
Date_last_updated28 Feb 2005 00:00:00
Automated_descriptionIs affected by several genes including daf-12; prg-1; and alg-1 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube and nicotine based on RNA-seq studies.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_transcriptD1007.17
D1007.17a
Experimental_infoRNAi_result (20)
Expression_clusterWBPaper00040221:DAF-12_target_ALF4
WBPaper00045019:MWCNT_upregulated
WBPaper00045316:prg-1_downregulated_L4
WBPaper00049006:nicotine_upregulated_F1
WBPaper00050163:chd-3(eh4)_upregulated_24-cell-embryo
WBPaper00050386:C.albicans_4h_upregulated
WBPaper00051404:alg-1(gk214)_upregulated_miRNA
WBPaper00051404:alg-5(ram2)_upregulated_miRNA
WBPaper00056284:ints-9(RNAi)_downregulated
WBPaper00057033:pry-1(mu38)_upregulated
WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
WBPaper00060445:nfki-1(cer1)_upregulated_L4
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
Map_infoPositiveInside_rearrnDf61
Positive_cloneD1007Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataPos_neg_data10934
Interpolated_map_positionI-1.04156
ReferenceWBPaper00024441
WBPaper00031335
RemarkThe annotation of cel-mir-353 as a microRNA was questioned by Jan et al (Nature 2011 469:97-101). The pattern of reads from deep sequencing datasets aggregated in miRBase and mapping to the locus is not consistent with microRNA processing. The sequence is removed from miRBase 21.
MethodGene