WormBase Tree Display for Gene: WBGene00007197
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WBGene00007197 | SMap | S_parent | Sequence | B0513 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | prdh-1 | Person_evidence | WBPerson2173 | |||||
Sequence_name | B0513.5 | ||||||||
Molecular_name | B0513.5a | ||||||||
B0513.5a.1 | |||||||||
CE37309 | |||||||||
B0513.5b | |||||||||
CE49937 | |||||||||
B0513.5b.1 | |||||||||
Other_name | prodh | Paper_evidence | WBPaper00050536 | ||||||
CELE_B0513.5 | Accession_evidence | NDB | BX284604 | ||||||
Public_name | prdh-1 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:47 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 11 Jun 2018 11:44:56 | WBPerson1983 | Name_change | CGC_name | prdh-1 | ||||
Status | Live | ||||||||
Gene_info (7) | |||||||||
Disease_info | Experimental_model | DOID:0060413 | Homo sapiens | Paper_evidence | WBPaper00047004 | ||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 20 Sep 2018 00:00:00 | ||||||||
Potential_model | DOID:0070080 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9453) | |||||
DOID:0080542 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9453) | ||||||
DOID:9252 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9453) | ||||||
Disease_relevance | 22q11.2 deletion syndrome (22q11.2DS) is the most common human deletion syndrome caused by deletion of a small piece of chromosome 22, characterized by neurodevelopmental defects, schizophrenia, congenital cardiac and craniofacial abnormalites (includes DiGeorge Syndrome and velocardiofacial syndrome); the 22q11.2 deletion overlaps several protein-coding genes including PRODH (Proline dehydrogenase (oxidase) 1); the C. elegans ortholog prdh-1 knockdown phenotypes include reduced accumulation rate of newly synthesized proteins, extended life span and increased thermo-tolerance. | Homo sapiens | Paper_evidence | WBPaper00047004 | |||||
Accession_evidence | OMIM | 611867 | |||||||
239500 | |||||||||
600850 | |||||||||
606810 | |||||||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 15 Sep 2015 00:00:00 | ||||||||
Models_disease_in_annotation | WBDOannot00000362 | ||||||||
Molecular_info | Corresponding_CDS | B0513.5a | |||||||
B0513.5b | |||||||||
Corresponding_CDS_history | B0513.5:wp131 | ||||||||
Corresponding_transcript | B0513.5a.1 | ||||||||
B0513.5b.1 | |||||||||
Other_sequence (25) | |||||||||
Associated_feature | WBsf998468 | ||||||||
WBsf998469 | |||||||||
WBsf998470 | |||||||||
WBsf231172 | |||||||||
Experimental_info | RNAi_result | WBRNAi00009831 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00000804 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00113437 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00039157 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1021073 | ||||||||
Expr1143312 | |||||||||
Expr2000233 | |||||||||
Expr2018453 | |||||||||
Drives_construct | WBCnstr00033926 | ||||||||
Construct_product | WBCnstr00033926 | ||||||||
Microarray_results (20) | |||||||||
Expression_cluster (140) | |||||||||
Interaction (13) | |||||||||
Map_info | Map | IV | Position | 10.894 | |||||
Positive | Positive_clone | B0513 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00038491 | ||||||||
WBPaper00049828 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00056909 | |||||||||
WBPaper00061547 | |||||||||
WBPaper00063976 | |||||||||
WBPaper00064064 | |||||||||
WBPaper00065331 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |