WormBase Tree Display for Gene: WBGene00006873

WBGene00006873 SMap: S_parent: Sequence: M142
  Identity (6)
  Gene_info: Biotype: SO:0001217
    Gene_class: vab
    Reference_allele: WBVar00144111
    Allele (137)
    Legacy_information: e1562 : hermaphrodite tail abnormal sometimes twisted tail whip never normal often bobbed; sometimes uncoordinated with bent tail; adult male tail deformed. ES3 ME0. NA1.
      See also e1562
      [C.elegansII] e1562 : hermaphrodite tail abnormal, sometimes twisted, tail whip never normal often bobbed; variably uncoordinated with bent tail; adult male tail deformed; abnormal positioning of Cpap descendants, etc.ES3 ME0. NA>4: ???. Cloned: encodes homolog of Drosophila homeoprotein even-skipped. Transcripts present in 4 posterior cells during gastrulation. [Hodgkin 1983; CB; NJ]
    Strain (12)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (41)
    Paralog (20)
    Structured_description: Concise_description: The vab-7 gene encodes an even-skipped-like homeodomain protein that is required for DB motoneuron identity and posterior DB axonal polarity. Paper_evidence: WBPaper00005153
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cell fate specification and negative regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in muscle cell; neurons; somatic nervous system; and tail hypodermis. Is an ortholog of human EVX1 (even-skipped homeobox 1) and EVX2 (even-skipped homeobox 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: M142.4
    Corresponding_transcript: M142.4.1
    Other_sequence (11)
    Associated_feature (20)
    Transcription_factor: WBTranscriptionFactor000480
  Experimental_info: RNAi_result (23)
    Expr_pattern (14)
    Drives_construct (11)
    Antibody: WBAntibody00000465
      WBAntibody00001230
    Microarray_results (20)
    Expression_cluster (102)
    Interaction: WBInteraction000000877
      WBInteraction000001813
      WBInteraction000001814
      WBInteraction000002649
      WBInteraction000003100
      WBInteraction000003153
      WBInteraction000003222
      WBInteraction000003384
      WBInteraction000003971
      WBInteraction000003972
      WBInteraction000004115
      WBInteraction000004116
      WBInteraction000004117
      WBInteraction000004118
      WBInteraction000005851
      WBInteraction000009381
      WBInteraction000009442
      WBInteraction000028331
      WBInteraction000028383
      WBInteraction000028427
      WBInteraction000028848
      WBInteraction000028849
      WBInteraction000029403
      WBInteraction000029462
      WBInteraction000031838
      WBInteraction000034192
      WBInteraction000035319
      WBInteraction000035650
      WBInteraction000036933
      WBInteraction000037748
      WBInteraction000038690
      WBInteraction000040567
      WBInteraction000043781
      WBInteraction000044368
      WBInteraction000044839
      WBInteraction000046787
      WBInteraction000047036
      WBInteraction000047476
      WBInteraction000048695
      WBInteraction000052054
      WBInteraction000139066
      WBInteraction000139116
      WBInteraction000145311
      WBInteraction000145312
      WBInteraction000165734
      WBInteraction000165766
      WBInteraction000166167
      WBInteraction000166376
      WBInteraction000166452
      WBInteraction000188271
      WBInteraction000398286
      WBInteraction000501626
      WBInteraction000501628
      WBInteraction000501629
      WBInteraction000502820
      WBInteraction000519296
      WBInteraction000526367
      WBInteraction000527323
      WBInteraction000527383
      WBInteraction000527485
      WBInteraction000527587
      WBInteraction000527645
      WBInteraction000527646
      WBInteraction000527746
      WBInteraction000528062
      WBInteraction000528295
      WBInteraction000529156
      WBInteraction000530378
      WBInteraction000530857
      WBInteraction000532134
      WBInteraction000533335
      WBInteraction000533967
      WBInteraction000534089
      WBInteraction000555656
  Map_info: Map: III Position: 5.5985 Error: 0.012395
    Well_ordered
    Positive: Inside_rearr: eDf2
        eDp6
        tDf1
      Positive_clone: M142 Author_evidence: Ahringer JA
          Inferred_automatically: From sequence, transcript, pseudogene data
    Negative: Outside_rearr: tDp1
        tDp2
    Mapping_data: 2_point: 226
        4719
        6180
        6181
        6182
        6183
      Multi_point (25)
      Pos_neg_data: 350
        1598
        5728
        5737
        5947
        8371
        8381
        8383
        8392
        8559
  Reference (80)
  Remark: Data extracted from Ahringer (1996) : e1562 is rescued by M142, and has sequence change R88op in M142.4, encoding homolog of Drosophila even-skipped
  Method: Gene