WormBase Tree Display for Gene: WBGene00000487

WBGene00000487 SMap: S_parent: Sequence: C23H5
  Identity: Version: 2
    Name: CGC_name: che-6 Person_evidence: WBPerson261
            WBPerson260
      Sequence_name: C23H5.7
      Molecular_name: C23H5.7
        C23H5.7.1
        CE52177
      Other_name: cng-4 Person_evidence: WBPerson260
        CELE_C23H5.7 Accession_evidence: NDB BX284604
      Public_name: che-6
    DB_info: Database: WormFlux gene WBGene00000487
        NDB locus_tag CELE_C23H5.7
        Panther gene CAEEL|WormBase=WBGene00000487|UniProtKB=O61827
          family PTHR45638
        NCBI gene 182823
        RefSeq protein NM_001356910.3
        TREEFAM TREEFAM_ID TF319048
        TrEMBL UniProtAcc O61827
        UniProt_GCRP UniProtAcc O61827
        OMIM gene 123825
            600053
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 15 Aug 2012 10:29:53 WBPerson2970 Event: Acquires_merge: WBGene00016026
              Name_change: Sequence_name: C23H5.7
                Other_name: cng-4
      Acquires_merge: WBGene00016026
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: che
    Reference_allele: WBVar00143765
    Allele (165)
    Legacy_information: e1126 : non-chemotactic to chloride ion; abnormal IL2 basal bodies. ES1 ME3. NA1.
      See also e1126
      [C.elegansII] e1126 : non-chemotactic to chloride ion; abnormal IL2 basal bodies. ES1 ME3. NA1. [Lewis and Hodgkin 1977]
    Strain: WBStrain00022728
      WBStrain00022733
      WBStrain00004250
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog: WBGene00068888 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00041056 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00036641 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00156108 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      CBOVI.g8797 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g16122 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g6191 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g21363 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP31.g4705 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP31.g4707 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g12975 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g6156 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP40.g16017 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00092.g4117 Caenorhabditis angaria From_analysis: WormBase-Compara
      Csp11.Scaffold570.g4225 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp11.Scaffold629.g10738 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01061.g18056 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_15565 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_016060 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g10794 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_40038300 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g9766 Caenorhabditis elegans From_analysis: WormBase-Compara
      ZFIN:ZDB-GENE-070912-292 Danio rerio From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-110408-39 Danio rerio From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-061005-1 Danio rerio From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-090312-66 Danio rerio From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      HGNC:2148 Homo sapiens From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      HGNC:2149 Homo sapiens From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      HGNC:2150 Homo sapiens From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      HGNC:2152 Homo sapiens From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      MGI:88436 Mus musculus From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      MGI:1341818 Mus musculus From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      RGD:2367 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      RGD:70948 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      RGD:619844 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      RGD:621815 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
    Paralog: WBGene00006526 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00006525 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000562 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000563 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00022295 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001171 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00006830 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Located in neuronal cell body. Expressed in ASEL; ASER; AWCL; and AWCR. Human ortholog(s) of this gene implicated in achromatopsia 2 and retinitis pigmentosa 49. Is an ortholog of several human genes including CNGA1 (cyclic nucleotide gated channel subunit alpha 1); CNGA2 (cyclic nucleotide gated channel subunit alpha 2); and CNGA3 (cyclic nucleotide gated channel subunit alpha 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:13399 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2150)
      DOID:0110377 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2148)
      DOID:0110007 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2150)
      DOID:10584 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2148)
  Molecular_info: Corresponding_CDS: C23H5.7
    Corresponding_CDS_history: C23H5.7:wp239
      C23H5.7:wp261
    Corresponding_transcript: C23H5.7.1
    Other_sequence: FG354142.1
      JI168297.1
    Associated_feature: WBsf995623
      WBsf1016860
  Experimental_info: RNAi_result: WBRNAi00076157 Inferred_automatically: RNAi_primary
      WBRNAi00041037 Inferred_automatically: RNAi_primary
      WBRNAi00011068 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11202
      Expr1145077
      Expr2009967
      Expr2028207
    Drives_construct: WBCnstr00018218
    Microarray_results (18)
    Expression_cluster (53)
  Map_info: Map: IV Position: -11.0452
    Positive: Positive_clone: C23H5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene