WormBase Tree Display for Gene: WBGene00000036
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WBGene00000036 | SMap | S_parent | Sequence | CHROMOSOME_I | |||
---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||
Name (5) | |||||||
DB_info | Database (11) | ||||||
Species | Caenorhabditis elegans | ||||||
History (2) | |||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | ace | ||||||
Reference_allele | WBVar00145393 | ||||||
Allele (145) | |||||||
Legacy_information | g72 : class B acetylcholinesterase reduced 98%; no behavioral phenotype alone (see ace-1). ES1 ME3. NA12 (g73 etc.). | ||||||
[C.elegansII] g72 : class B acetylcholinesterase reduced 98%; no behavioral phenotype alone (see ace-1). ES1 ME3. OA11: g73 etc. [Culotti et al. 1981] | |||||||
Strain | WBStrain00022541 | ||||||
WBStrain00024339 | |||||||
WBStrain00032627 | |||||||
WBStrain00040622 | |||||||
WBStrain00007852 | |||||||
WBStrain00007853 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (23) | |||||||
Ortholog (57) | |||||||
Paralog (41) | |||||||
Structured_description | Concise_description | An acetylcholineesterase involved in the termination of cholinergic nerve transmission; it is predominantly expressed in motoneurons. | Paper_evidence | WBPaper00004932 | |||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Enables acetylcholinesterase activity and protein homodimerization activity. Involved in acetylcholine catabolic process; cholinergic synaptic transmission; and regulation of locomotion. Predicted to be located in extracellular space and plasma membrane. Expressed in several structures, including command interneuron; neurons; pm5; somatic nervous system; and tail hypodermis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Huntington's disease; artery disease (multiple); and diabetes mellitus (multiple). Is an ortholog of human BCHE (butyrylcholinesterase). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (15) | ||||||
Molecular_info | Corresponding_CDS | Y44E3A.2 | |||||
Corresponding_CDS_history | Y44E3A.2a:wp264 | ||||||
Y44E3A.2b:wp264 | |||||||
Corresponding_transcript | Y44E3A.2.1 | ||||||
Y44E3A.2.2 | |||||||
Other_sequence (77) | |||||||
Associated_feature (13) | |||||||
Experimental_info | RNAi_result | WBRNAi00027756 | Inferred_automatically | RNAi_primary | |||
WBRNAi00056556 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr2633 | ||||||
Expr12715 | |||||||
Expr1017666 | |||||||
Expr1030016 | |||||||
Expr1160030 | |||||||
Expr2009143 | |||||||
Expr2027380 | |||||||
Drives_construct (19) | |||||||
Construct_product | WBCnstr00009876 | ||||||
WBCnstr00022777 | |||||||
Regulate_expr_cluster | WBPaper00044452:ace_1_ace-2_downregulated | ||||||
WBPaper00044452:ace_1_ace-2_upregulated | |||||||
Microarray_results (18) | |||||||
Expression_cluster (108) | |||||||
Interaction (41) | |||||||
Map_info | Map | I | Position | -3.85604 | Error | 0.023989 | |
Well_ordered | |||||||
Positive | Positive_clone | Y44E3A | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | 2_point | 1019 | |||||
3681 | |||||||
Multi_point | 815 | ||||||
3202 | |||||||
3204 | |||||||
4026 | |||||||
5317 | |||||||
Pos_neg_data | 8067 | ||||||
8532 | |||||||
Reference (85) | |||||||
Method | Gene |