WormBase Tree Display for Gene: WBGene00000902
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WBGene00000902 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F31F6 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | daf-6 | Person_evidence | WBPerson521 | |||||
Sequence_name | F31F6.5 | ||||||||
Molecular_name | F31F6.5 | ||||||||
F31F6.5.1 | |||||||||
CE38955 | |||||||||
Other_name | ptr-7 | Paper_evidence | WBPaper00010276 | ||||||
Person_evidence | WBPerson576 | ||||||||
CELE_F31F6.5 | Accession_evidence | NDB | BX284606 | ||||||
Public_name | daf-6 | ||||||||
DB_info | Database | AceView | gene | XP511 | |||||
WormQTL | gene | WBGene00000902 | |||||||
WormFlux | gene | WBGene00000902 | |||||||
NDB | locus_tag | CELE_F31F6.5 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000902|UniProtKB=Q19945 | |||||||
family | PTHR10796 | ||||||||
NCBI | gene | 181584 | |||||||
RefSeq | protein | NM_078071.8 | |||||||
TREEFAM | TREEFAM_ID | TF331806 | |||||||
TrEMBL | UniProtAcc | Q19945 | |||||||
UniProt_GCRP | UniProtAcc | Q19945 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | daf | ||||||||
Reference_allele | WBVar00143954 | ||||||||
Allele (96) | |||||||||
Legacy_information | e1377 : defective dauer formation (daf-1 daf-2 suppressible) abnormal chemotaxis defective osmotic avoidance poor male mating; abnormal sensory anatomy especially amphidial sheath cells; no FITC uptake by amphids or phasmids. ES1 ME2. NA1. | ||||||||
See also e1377 | |||||||||
[C.elegansII] e1377 : defective dauer formation; abnormal chemotaxis; defective osmotic avoidance; poor male mating; abnormal sensory anatomy especially amphidial sheath cells (resembles Che-14); Dyf, no FITC uptake by amphids or phasmids. ES1 ME2. OA6. [Perkins et al. 1986; Starich et al. 1995; DR; SP] | |||||||||
Strain | WBStrain00004313 | ||||||||
WBStrain00004378 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (14) | |||||||||
Ortholog (33) | |||||||||
Paralog (30) | |||||||||
Structured_description | Concise_description | daf-6 encodes a Patched-related protein; daf-6 is required for amphid channel morphogenesis and thus, also for normal morphology of the outer labial sensilla; specifically, daf-6 is required for restricting the amphid sensory compartment diameter; daf-6 mutants display defects in several neuron-mediated functions including dauer larvae formation, chemotaxis, osmotic avoidance, male mating, negative regulation of lifespan, negative regulation of the neuron ASJ's axonal growth late in development, and dye uptake by amphids and phasmids; a DAF-6::GFP is expressed in the amphid sheath and socket cells and in the excretory canal. | Paper_evidence (11) | ||||||
Person_evidence | WBPerson261 | ||||||||
Curator_confirmed | WBPerson13481 | ||||||||
WBPerson1843 | |||||||||
WBPerson567 | |||||||||
Date_last_updated | 24 Oct 2011 00:00:00 | ||||||||
Automated_description | Involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of dauer larval development; and regulation of insulin receptor signaling pathway. Located in cytoplasmic vesicle and plasma membrane. Expressed in several structures, including cuticle; excretory system; interfacial epithelial cell; neurons; and vulval cell. Is an ortholog of human PTCHD3 (patched domain containing 3 (gene/pseudogene)). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F31F6.5 | |||||||
Corresponding_CDS_history | F31F6.5:wp146 | ||||||||
Corresponding_transcript | F31F6.5.1 | ||||||||
Other_sequence | MA00829 | ||||||||
Dviv_isotig25805 | |||||||||
GR13379 | |||||||||
GRC01680_1 | |||||||||
JI166574.1 | |||||||||
Oden_isotig23367 | |||||||||
MAC00273_1 | |||||||||
Oden_isotig25088 | |||||||||
Associated_feature | WBsf648771 | ||||||||
WBsf663603 | |||||||||
WBsf663604 | |||||||||
WBsf718778 | |||||||||
WBsf718779 | |||||||||
WBsf718780 | |||||||||
WBsf718781 | |||||||||
WBsf1008031 | |||||||||
WBsf236735 | |||||||||
Experimental_info | RNAi_result | WBRNAi00076947 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00014181 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00076915 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00046060 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr3510 | ||||||||
Expr3511 | |||||||||
Expr3897 | |||||||||
Expr8603 | |||||||||
Expr12301 | |||||||||
Expr1016907 | |||||||||
Expr1030566 | |||||||||
Expr1149951 | |||||||||
Expr2010781 | |||||||||
Expr2029018 | |||||||||
Drives_construct (9) | |||||||||
Construct_product | WBCnstr00000949 | ||||||||
WBCnstr00006566 | |||||||||
WBCnstr00006567 | |||||||||
WBCnstr00006570 | |||||||||
WBCnstr00011444 | |||||||||
WBCnstr00013396 | |||||||||
WBCnstr00022848 | |||||||||
WBCnstr00037208 | |||||||||
Microarray_results (19) | |||||||||
Expression_cluster (190) | |||||||||
Interaction (66) | |||||||||
Map_info | Map | X | Position | 21.5043 | Error | 0.013514 | |||
Positive | Positive_clone | F31F6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | 2_point | 283 | |||||||
419 | |||||||||
420 | |||||||||
421 | |||||||||
Multi_point | 649 | ||||||||
4318 | |||||||||
4508 | |||||||||
Pos_neg_data | 2161 | ||||||||
2169 | |||||||||
2228 | |||||||||
8330 | |||||||||
Reference (109) | |||||||||
Picture | WBPicture0000013046 | ||||||||
Remark | Previous sequence connection to C54A12.1 as well as positive clone C54A12 were incorrect [030311 ck1] | ||||||||
ptr-7 has been merged with this gene following advice of CGC [krb 030512] | |||||||||
This gene previously listed ptr-6 as an other name. This association was probably incorrect and has been removed [krb 030512] | |||||||||
Method | Gene |