WormBase Tree Display for Gene: WBGene00004882
expand all nodes | collapse all nodes | view schema
WBGene00004882 | SMap | S_parent | Sequence | F46B6 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | smg | ||||||
Reference_allele | WBVar00088765 | ||||||
Allele (31) | |||||||
Legacy_information | See also ma116 | ||||||
[C.elegansII] ma116 : adult male has swollen bursa, adult hermaphrodite has protruding vulva. ME1. Recessive suppressor of unc-54(r293),tra-2(e1209), etc.; suppression reduced bymaternal rescue. unc-54 nonsense RNAs accumulate. OA3: r1181, e2615psu, e2616psu. Cloned: YAC and phage rescue. [Hodgkin et al. 1989; Pulak and Anderson 1993; CB; TR] | |||||||
Strain | WBStrain00034951 | ||||||
WBStrain00004551 | |||||||
WBStrain00004567 | |||||||
WBStrain00051118 | |||||||
WBStrain00055592 | |||||||
WBStrain00055594 | |||||||
WBStrain00055593 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (13) | |||||||
Contained_in_operon | CEOP5236 | ||||||
Ortholog (30) | |||||||
Structured_description | Automated_description | Predicted to enable mRNA binding activity. Involved in male genitalia development; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and obsolete hermaphrodite genitalia development. Located in nucleus and perinuclear region of cytoplasm. Expressed in intestinal cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 14. Is an ortholog of human UPF3A (UPF3A regulator of nonsense mediated mRNA decay) and UPF3B (UPF3B regulator of nonsense mediated mRNA decay). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0060821 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20439) | ||
Molecular_info | Corresponding_CDS (2) | ||||||
Corresponding_CDS_history | F46B6.3:wp46 | ||||||
F46B6.3:wp69 | |||||||
F46B6.3b:wp76 | |||||||
Corresponding_transcript | F46B6.3a.1 | ||||||
F46B6.3b.1 | |||||||
Other_sequence | CBC05396_1 | ||||||
Associated_feature | WBsf234278 | ||||||
WBsf234279 | |||||||
Experimental_info | RNAi_result | WBRNAi00094500 | Inferred_automatically | RNAi_primary | |||
WBRNAi00008069 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00047495 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00085061 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00094403 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00015065 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00047493 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00094395 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr110 | ||||||
Expr1337 | |||||||
Expr1022685 | |||||||
Expr1032421 | |||||||
Expr1151332 | |||||||
Expr2015910 | |||||||
Expr2034143 | |||||||
Drives_construct | WBCnstr00010227 | ||||||
WBCnstr00035343 | |||||||
Construct_product | WBCnstr00035343 | ||||||
Antibody | WBAntibody00001272 | ||||||
Microarray_results (28) | |||||||
Expression_cluster (112) | |||||||
Interaction (50) | |||||||
Map_info | Map | V | Position | 2.19411 | Error | 0.006525 | |
Well_ordered | |||||||
Positive | Inside_rearr | eDf1 | |||||
Positive_clone | F46B6 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
Mapping_data | 2_point | 3387 | |||||
Multi_point | 1192 | ||||||
3101 | |||||||
3102 | |||||||
5376 | |||||||
Pos_neg_data | 4574 | ||||||
4575 | |||||||
Reference (38) | |||||||
Method | Gene |