WormBase Tree Display for Gene: WBGene00006868
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WBGene00006868 | SMap | S_parent | Sequence | M03A1 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | vab-1 | Person_evidence | WBPerson261 | |||||
Sequence_name | M03A1.1 | ||||||||
Molecular_name | M03A1.1 | ||||||||
M03A1.1.1 | |||||||||
CE25060 | |||||||||
Other_name | CELE_M03A1.1 | Accession_evidence | NDB | BX284602 | |||||
Public_name | vab-1 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | vab | ||||||||
Reference_allele | WBVar00142901 | ||||||||
Allele (418) | |||||||||
Legacy_information (3) | |||||||||
Strain (24) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (38) | |||||||||
Ortholog (113) | |||||||||
Paralog (69) | |||||||||
Structured_description | Concise_description | vab-1 encodes an ephrin receptor; during development, vab-1 activity is required for neural and epithelial morphogenesis as well as for proper axon targeting and neuronal cell migration; in addition, VAB-1 functions as a major sperm protein receptor in a sperm-sensing control mechanism that regulates oocyte meiotic maturation; VAB-1::GFP reporters are expressed in neuronal cells and in oocytes and sheath cells of the proximal gonad. | Paper_evidence | WBPaper00003020 | |||||
WBPaper00003843 | |||||||||
WBPaper00005670 | |||||||||
WBPaper00027013 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 28 Feb 2007 00:00:00 | ||||||||
Automated_description | Enables ephrin receptor activity and protein domain specific binding activity. Involved in several processes, including cell development; embryonic morphogenesis; and regulation of axon guidance. Located in axon and plasma membrane. Expressed in several structures, including hypodermal cell; neuroblasts; neurons; oocyte; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; aortic dissection; cataract 6 multiple types; and gastrointestinal system cancer (multiple). Is an ortholog of several human genes including EPHB1 (EPH receptor B1); EPHB2 (EPH receptor B2); and EPHB3 (EPH receptor B3). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model (14) | ||||||||
Molecular_info | Corresponding_CDS | M03A1.1 | |||||||
Corresponding_CDS_history | M03A1.1b:wp274 | ||||||||
Corresponding_transcript | M03A1.1.1 | ||||||||
Other_sequence (11) | |||||||||
Associated_feature (54) | |||||||||
Experimental_info (10) | |||||||||
Map_info | Map | II | Position | -3.85469 | Error | 0.013028 | |||
Well_ordered | |||||||||
Positive | Inside_rearr | mDf14 | |||||||
mDf15 | |||||||||
Positive_clone | M03A1 | Person_evidence | WBPerson105 | ||||||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
Mapping_data | 2_point | 266 | |||||||
Multi_point | 48 | ||||||||
881 | |||||||||
882 | |||||||||
1880 | |||||||||
4031 | |||||||||
4032 | |||||||||
Pos_neg_data (12) | |||||||||
Reference (154) | |||||||||
Method | Gene |